Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29814510 | 0.90 | GPR119 (0.51) | GPR119ALDH1A1LMNACYP11B2SMN1; SMN2 | |
| SCHEMBL7694218 | 0.90 | GPR119 (0.51) | GPR119ALDH1A1LMNACYP11B2SMN1; SMN2 | |
| SCHEMBL25447371 | 0.85 | GPR119 (0.46) | GPR119CYP11B2GRM1 | |
| SCHEMBL21523808 | 0.85 | RORC (0.47) | GPR119CYP11B2PKM | |
| SCHEMBL2277942 | 0.83 | ALDH1A1 (0.55) | GPR119ALDH1A1LMNACYP11B2SMN1; SMN2 | |
| SCHEMBL2629481 | 0.83 | ALDH1A1 (0.60) | GPR119ALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL25269330 | 0.81 | GPR119 (0.48) | GPR119ALDH1A1LMNACYP11B2SMN1; SMN2 | |
| SCHEMBL30488179 | 0.81 | GPR119 (0.48) | GPR119ALDH1A1LMNACYP11B2SMN1; SMN2 | |
| SCHEMBL640760 | 0.81 | ALDH1A1 (0.53) | GPR119ALDH1A1LMNACYP11B2SMN1; SMN2 | |
| SCHEMBL31654383 | 0.81 | GPR119 (0.49) | GPR119ALDH1A1LMNACYP11B2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107547-A2 | AZETIDINE AND SPIROAZETIDINE COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |