SCHEMBL25259709

SCHEMBL25259709

Cc1c2c(nn1S(=O)(=O)c1ccc(F)cc1)-c1ccccc1C(=O)C2=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TP53 P04637 1/20 0.44
▸ KMT2A Q03164 5/20 0.43
▸ LMNA P02545 6/20 0.41
▸ MAPT P10636 4/20 0.41
▸ SMN1; SMN2 Q16637 3/20 0.41
▸ GAA P10253 2/20 0.41
▸ HTT P42858 2/20 0.41
▸ NPSR1 Q6W5P4 2/20 0.41
▸ ALDH1A1 P00352 2/20 0.41
▸ MEN1 O00255 3/20 0.40
▸ ALDH3A1 P30838 2/20 0.40
▸ TSHR P16473 1/20 0.40
▸ MAPK1 P28482 1/20 0.40
▸ PTGS2 P35354 2/20 0.38
▸ PKM P14618 1/20 0.38
▸ NPC1 O15118 1/20 0.37
▸ MAOB P27338 1/20 0.37
▸ CASP3 P42574 1/20 0.37
▸ RAB9A P51151 1/20 0.37
▸ SENP8 Q96LD8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29405020 1.00 TP53 (0.44) TP53KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL25253327 0.90 NR1H2 (0.45) TP53KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL29405655 0.90 NR1H2 (0.45) TP53KMT2ALMNAMAPTSMN1; SMN2
SCHEMBL29404553 0.89 KMT2A (0.42) KMT2AMAPTSMN1; SMN2HTTALDH1A1
SCHEMBL25259052 0.89 KMT2A (0.42) KMT2AMAPTSMN1; SMN2HTTALDH1A1
SCHEMBL25257867 0.87 MEN1 (0.47) KMT2AMAPTSMN1; SMN2NPSR1ALDH1A1
SCHEMBL29402620 0.87 MEN1 (0.47) KMT2AMAPTSMN1; SMN2NPSR1ALDH1A1
SCHEMBL25256995 0.86 MEN1 (0.44) KMT2ALMNAMAPTSMN1; SMN2HTT
SCHEMBL25256645 0.86 LMNA (0.41) KMT2ALMNAMAPTGAAALDH1A1
SCHEMBL29404853 0.86 LMNA (0.41) KMT2ALMNAMAPTGAAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12570613-B2 Imidazoquinoline or benzoindazolone compound and intermediate for preparing same LMITO THERAPEUTICS INC. (KR) 2026-03-10 — — US claimed
US-20240034719-A1 IMIDAZOQUINOLINE OR BENZOINDAZOLONE COMPOUND AND INTERMEDIATE FOR PREPARING SAME LMITO THERAPEUTICS INC. (KR) 2024-02-01 — — US claimed
EP-4212530-A1 IMIDAZOLQUINOLINE OR BENZOINDAZOLONE COMPOUND AND INTERMEDIATE FOR PREPARING SAME Lmito Therapeutics Inc. (KR) 2023-07-19 — — EP claimed
US-12570613-B2 Imidazoquinoline or benzoindazolone compound and intermediate for preparing same LMITO THERAPEUTICS INC. (KR) 2026-03-10 — — US disclosed
US-20240034719-A1 IMIDAZOQUINOLINE OR BENZOINDAZOLONE COMPOUND AND INTERMEDIATE FOR PREPARING SAME LMITO THERAPEUTICS INC. (KR) 2024-02-01 — — US disclosed
EP-4212530-A1 IMIDAZOLQUINOLINE OR BENZOINDAZOLONE COMPOUND AND INTERMEDIATE FOR PREPARING SAME Lmito Therapeutics Inc. (KR) 2023-07-19 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240034719-A1 IMIDAZOQUINOLINE OR BENZOINDAZOLONE COMPOUND AND INTERMEDIATE FOR PREPARING SAME NQO1, NFE2L2, KEAP1 TP53 630/4885KMT2A 2259/4885LMNA 785/4885
US-12570613-B2 Imidazoquinoline or benzoindazolone compound and intermediate for preparing same NQO1, CBR1, NFE2L2 TP53 2086/4885KMT2A 3455/4885LMNA 620/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback