Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | CTSV | O60911 | 3/20 | 0.51 |
| ▸ | CTSL | P07711 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | F10 | P00742 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | F7 | P08709 | 1/20 | 0.45 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6433972 | 0.96 | ALDH1A1 (0.54) | ALDH1A1HSD17B10MAPK1CASP1CASP7 | |
| SCHEMBL17181501 | 0.88 | ALDH1A1 (0.59) | ALDH1A1HSD17B10MAPK1CASP1CASP7 | |
| SCHEMBL12663537 | 0.88 | ALDH1A1 (0.54) | ALDH1A1HSD17B10MAPK1CASP1CASP7 | |
| SCHEMBL374339 | 0.86 | ALDH1A1 (0.67) | ALDH1A1HSD17B10MAPK1CASP1CASP7 | |
| SCHEMBL1890489 | 0.85 | ALDH1A1 (0.49) | ALDH1A1HSD17B10MAPK1CASP1CASP7 | |
| SCHEMBL6431150 | 0.85 | ALDH1A1 (0.51) | ALDH1A1HSD17B10MAPK1CASP1CASP7 | |
| SCHEMBL12003807 | 0.81 | ALDH1A1 (0.67) | ALDH1A1HSD17B10MAPK1CTSVCTSL | |
| SCHEMBL5649656 | 0.80 | ALDH1A1 (0.56) | ALDH1A1HSD17B10MAPK1CASP1CASP7 | |
| SCHEMBL23887906 | 0.79 | ALDH1A1 (0.74) | ALDH1A1HSD17B10MAPK1CASP1CASP7 | |
| SCHEMBL20032548 | 0.78 | ALDH1A1 (0.64) | ALDH1A1HSD17B10MAPK1CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12595245-B2 | Inhibitors of MET kinase | CELYN THERAPEUTICS, INC. (US) | 2026-04-07 | — | — | US | disclosed |
| EP-4448510-A1 | INHIBITORS OF MET KINASE | Kinnate Biopharma Inc. (US) | 2024-10-23 | — | — | EP | disclosed |
| CN-118742542-A | Inhibitors of MET kinase | 金耐特生物制药公司 | 2024-10-01 | — | — | CN | disclosed |
| US-20240067626-A1 | INHIBITORS OF MET KINASE | CELYN THERAPEUTICS, INC. | 2024-02-29 | — | — | US | disclosed |
| US-11753395-B2 | Inhibitors of MET kinase | KINNATE BIOPHARMA INC. (US) | 2023-09-12 | — | — | US | disclosed |
| US-20230219929-A1 | INHIBITORS OF MET KINASE | CELYN THERAPEUTICS, INC. | 2023-07-13 | — | — | US | disclosed |
| WO-2023114809-A1 | INHIBITORS OF MET KINASE | KINNATE BIOPHARMA INC. (US) | 2023-06-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12595245-B2 | Inhibitors of MET kinase | MET, ABL1, ERBB2 | ALDH1A1 2585/4885HSD17B10 4291/4885MAPK1 338/4885 |
| US-20230219929-A1 | INHIBITORS OF MET KINASE | MET, RET, MERTK | ALDH1A1 2071/4885HSD17B10 3607/4885MAPK1 555/4885 |
| US-11753395-B2 | Inhibitors of MET kinase | MET, RET, MERTK | ALDH1A1 2071/4885HSD17B10 3607/4885MAPK1 555/4885 |
| US-20240067626-A1 | INHIBITORS OF MET KINASE | MET, RET, MERTK | ALDH1A1 2071/4885HSD17B10 3607/4885MAPK1 555/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.