Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 18/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 2/20 | 0.54 |
| ▸ | CASP7 | P55210 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL374339 | 0.88 | ALDH1A1 (0.67) | ALDH1A1HSD17B10MAPK1CASP1CASP7 | |
| SCHEMBL16619650 | 0.87 | ALDH1A1 (0.52) | ALDH1A1HSD17B10MAPK1CASP1CASP7 | |
| SCHEMBL6431219 | 0.85 | ALDH1A1 (0.50) | ALDH1A1HSD17B10MAPK1CASP1CASP7 | |
| SCHEMBL6433972 | 0.84 | ALDH1A1 (0.54) | ALDH1A1HSD17B10MAPK1CASP1CASP7 | |
| SCHEMBL17675496 | 0.84 | ALDH1A1 (0.48) | ALDH1A1HSD17B10MAPK1CASP1CASP7 | |
| SCHEMBL6430655 | 0.83 | ALDH1A1 (0.48) | ALDH1A1HSD17B10MAPK1CASP1CASP7 | |
| SCHEMBL6431158 | 0.82 | TSHR (0.47) | ALDH1A1HSD17B10MAPK1CASP1CASP7 | |
| SCHEMBL20032548 | 0.80 | ALDH1A1 (0.64) | ALDH1A1HSD17B10MAPK1CASP1CASP7 | |
| SCHEMBL25260320 | 0.80 | ALDH1A1 (0.54) | ALDH1A1HSD17B10MAPK1CASP1CASP7 | |
| SCHEMBL6431438 | 0.79 | ALDH1A1 (0.62) | ALDH1A1HSD17B10MAPK1CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070299092-A1 | Quinone Substituted Quinazoline and Quinoline Kinase Inhibitors | WYETH (US) | 2007-12-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070299092-A1 | Quinone Substituted Quinazoline and Quinoline Kinase Inhibitors | KDR, FLT1, FLT4 | ALDH1A1 530/4885HSD17B10 2150/4885MAPK1 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.