Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5243760 | 0.88 | KMT2A (0.61) | EPHX2GAACYP2C19KMT2ASMN1; SMN2 | |
| SCHEMBL5243710 | 0.83 | EPHX2 (0.77) | EPHX2HSD11B1KMT2AALDH1A1MEN1 | |
| SCHEMBL4964697 | 0.82 | CNR1 (0.61) | EPHX2KMT2AMEN1KDM4E | |
| SCHEMBL613101 | 0.82 | EPHX2 (0.79) | EPHX2HSD11B1KMT2AALDH1A1MEN1 | |
| SCHEMBL24781397 | 0.81 | KMT2A (0.57) | KMT2AALDH1A1MEN1HTTPOLB | |
| SCHEMBL24781390 | 0.81 | KMT2A (0.57) | KMT2AALDH1A1MEN1HTTPOLB | |
| SCHEMBL24781392 | 0.81 | KMT2A (0.57) | KMT2AALDH1A1MEN1HTTPOLB | |
| SCHEMBL21670262 | 0.81 | LMNA (0.70) | CYP2C19ALDH1A1HTTSMN1; SMN2TSHR | |
| SCHEMBL612150 | 0.80 | EPHX2 (0.66) | EPHX2GAAHSD11B1KMT2AALDH1A1 | |
| SCHEMBL612149 | 0.80 | EPHX2 (0.66) | EPHX2GAAHSD11B1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192816-A1 | COMPOUNDS AS C5AR INHIBITORS | Kira Pharmaceuticals (Suzhou) Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |