Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 9/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3974715 | 0.85 | EPHX2 (0.65) | CNR1MEN1KMT2AEPHX2 | |
| SCHEMBL25261069 | 0.82 | EPHX2 (0.53) | MEN1KMT2AEPHX2KDM4E | |
| SCHEMBL4705021 | 0.82 | MEN1 (0.65) | CNR1MEN1KMT2AEPHX2AKR1C3 | |
| SCHEMBL610753 | 0.81 | EPHX2 (0.67) | CNR1MEN1KMT2AEPHX2 | |
| SCHEMBL610754 | 0.81 | EPHX2 (0.67) | CNR1MEN1KMT2AEPHX2 | |
| SCHEMBL7306841 | 0.81 | AKR1C3 (0.62) | CNR1MEN1KMT2AEPHX2AKR1C3 | |
| SCHEMBL4292842 | 0.80 | EPHX2 (0.78) | CNR1MEN1KMT2AEPHX2 | |
| SCHEMBL4292847 | 0.80 | EPHX2 (0.78) | CNR1MEN1KMT2AEPHX2 | |
| SCHEMBL24781390 | 0.80 | KMT2A (0.57) | MEN1KMT2A | |
| SCHEMBL24781397 | 0.80 | KMT2A (0.57) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758580-A4 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORP (US) | 2008-01-16 | — | — | EP | claimed |
| EP-1758580-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | Incyte Corporation (US) | 2007-03-07 | — | — | EP | claimed |
| WO-2006012226-A2 | N-SUBSTITUTED PIPERIDINES AND THEIR USE AS PHARMACEUTICALS | INCYTE CORPORATION (US) | 2006-02-02 | — | — | WO | claimed |
| EP-4192816-A1 | COMPOUNDS AS C5AR INHIBITORS | Kira Pharmaceuticals (Suzhou) Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |