Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | DGKA | P23743 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 6/20 | 0.53 |
| ▸ | HTR2C | P28335 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7267842 | 1.00 | NAAA (0.55) | NAAADGKAACHEHTR2CPRSS1 | |
| SCHEMBL2525587 | 1.00 | NAAA (0.55) | NAAADGKAACHEHTR2CPRSS1 | |
| SCHEMBL2527254 | 0.98 | NAAA (0.52) | NAAADGKAACHEHTR2CPRSS1 | |
| SCHEMBL1362236 | 0.91 | DGKA (0.54) | NAAADGKAACHEHTR2CPRSS1 | |
| SCHEMBL420094 | 0.91 | NAAA (0.64) | NAAADGKAACHEHTR2CPRSS1 | |
| Pentane-1,5-Dibutanoate SCHEMBL15705199 | 0.91 | NAAA (0.64) | NAAADGKAACHEHTR2CPRSS1 | |
| SCHEMBL2529579 | 0.90 | DGKA (0.64) | NAAADGKAACHEHTR2CPRSS1 | |
| SCHEMBL34462705 | 0.90 | DGKA (0.64) | NAAADGKAACHEHTR2CPRSS1 | |
| SCHEMBL2531856 | 0.90 | DGKA (0.64) | NAAADGKAACHEHTR2CPRSS1 | |
| SCHEMBL421653 | 0.89 | NAAA (0.60) | NAAADGKAACHEHTR2CPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |
| CN-1905857-A | Controlled release of topiramate in liquid dosage forms | ALZA CORP (US) | 2007-01-31 | — | — | CN | disclosed |