Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.60 |
| ▸ | DGKA | P23743 | 1/20 | 0.60 |
| ▸ | HTR2C | P28335 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.48 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pentane-1,5-Dibutanoate SCHEMBL15705199 | 0.97 | NAAA (0.64) | NAAADGKAHTR2CALDH1A1RAD52 | |
| SCHEMBL420094 | 0.97 | NAAA (0.64) | NAAADGKAHTR2CALDH1A1RAD52 | |
| SCHEMBL117196 | 0.95 | NAAA (0.68) | NAAADGKAHTR2CALDH1A1RAD52 | |
| SCHEMBL1871180 | 0.95 | NAAA (0.68) | NAAADGKAHTR2CALDH1A1RAD52 | |
| SCHEMBL5930623 | 0.95 | DGKA (0.60) | NAAADGKAHTR2CALDH1A1RAD52 | |
| SCHEMBL1171560 | 0.93 | NAAA (0.72) | NAAADGKAHTR2CRAD52NPSR1 | |
| SCHEMBL2891994 | 0.93 | NAAA (0.72) | NAAADGKAHTR2CRAD52NPSR1 | |
| SCHEMBL128168 | 0.93 | NAAA (0.72) | NAAADGKAHTR2CRAD52NPSR1 | |
| SCHEMBL10149466 | 0.93 | NAAA (0.72) | NAAADGKAHTR2CRAD52NPSR1 | |
| SCHEMBL21044646 | 0.93 | NAAA (0.72) | NAAADGKAHTR2CRAD52NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102171228-B | Method for producing mono-hydroxy-functionalized dialkylphosphinic acids, esters and salts by means of vinyl esters of carboxylic acids and use thereof | CLARIANT FINANCE BVI LTD | 2015-03-25 | — | — | CN | claimed |
| CN-102171227-B | Method for producing mono-carboxy-functionalized dialkylphosphinic acids, esters and salts using a vinyl ester of a carboxylic acid and the use thereof | CLARIANT INT LTD | 2014-11-12 | — | — | CN | claimed |
| CN-102171228-A | Method for producing mono-hydroxy-functionalized dialkylphosphinic acids, esters and salts by means of vinyl esters of carboxylic acids and use thereof | CLARIANT INT LTD | 2011-08-31 | — | — | CN | claimed |
| CN-102171227-A | Method for producing mono-carboxy-functionalized dialkylphosphinic acids, esters and salts using a vinyl ester of a carboxylic acid and the use thereof | CLARIANT INT LTD | 2011-08-31 | — | — | CN | claimed |
| US-9700627-B2 | Biodegradable poly (beta-amino esters) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2017-07-11 | — | — | US | disclosed |
| US-9481658-B2 | Optical film, retardation plate, elliptica polarizing plate, liquid crystal display device and compound | FUJIFILM CORPORATION (JP) | 2016-11-01 | — | — | US | disclosed |
| US-20160022821-A1 | BIODEGRADABLE POLY (BETA-AMINO ESTERS) AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-01-28 | — | — | US | disclosed |
| US-9101666-B2 | Biodegradable poly(beta-amino esters) and uses thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2015-08-11 | — | — | US | disclosed |
| CN-102171228-B | Method for producing mono-hydroxy-functionalized dialkylphosphinic acids, esters and salts by means of vinyl esters of carboxylic acids and use thereof | CLARIANT FINANCE BVI LTD | 2015-03-25 | — | — | CN | disclosed |
| US-20150080582-A1 | OPTICAL FILM, RETARDATION PLATE, ELLIPTICA POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE AND COMPOUND | FUJIFILM CORPORATION (JP) | 2015-03-19 | — | — | US | disclosed |
| CN-102164933-B | Process for preparing mono-carboxy-functionalized dialkylphosphinic acids, esters and salts by means of alkylene oxides and use thereof | CLARIANT INT LTD | 2014-12-10 | — | — | CN | disclosed |
| CN-102171227-B | Method for producing mono-carboxy-functionalized dialkylphosphinic acids, esters and salts using a vinyl ester of a carboxylic acid and the use thereof | CLARIANT INT LTD | 2014-11-12 | — | — | CN | disclosed |
| US-20100036084-A1 | BIODEGRADABLE POLY(BETA-AMINO ESTERS) AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-02-11 | — | — | US | disclosed |
| US-20080242626-A1 | End-Modified Poly(beta-amino esters) and Uses Thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-10-02 | — | — | US | disclosed |
| US-7427394-B2 | Delivering labile agents; buffering effect; transfecting nucleic acids; nontoxic | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-09-23 | — | — | US | disclosed |
| US-20080145338-A1 | Acrylate-terminated poly(beta-amino esters); high throughput assay; biocompatability | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-06-19 | — | — | US | disclosed |
| US-7361451-B2 | Lithographic printing plate precursor and lithographic printing method using the same | FUJIFILM CORPORATION (JP) | 2008-04-22 | — | — | US | disclosed |
| US-7350917-B2 | Light control plastic lens, coated sheet-like light control element for the lens production, and a production method for light control plastic lens | MGC FILSEET CO., LTD. (JP) | 2008-04-01 | — | — | US | disclosed |
| US-20050168690-A1 | Light control plastic lens, coated sheet-like light control element for the lens production, and a production method for light control plastic lens | FUJI KASEI CO., LTD. (JP) | 2005-08-04 | — | — | US | disclosed |
| EP-1560060-A1 | Polarizing or photochromic plastic lens, coated sheet-like light element and method of its production | Fuji Kasei Co., Ltd. (JP) | 2005-08-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080145338-A1 | Acrylate-terminated poly(beta-amino esters); high throughput assay; biocompatability | ACP1, ILK, BCAT2 | NAAA 797/4885DGKA 2497/4885HTR2C 2267/4885 |
| US-20160022821-A1 | BIODEGRADABLE POLY (BETA-AMINO ESTERS) AND USES THEREOF | PARN, PARG, NPEPPS | NAAA 74/4885DGKA 3262/4885HTR2C 4535/4885 |
| US-20080242626-A1 | End-Modified Poly(beta-amino esters) and Uses Thereof | PARN, PARG, POLL | NAAA 197/4885DGKA 1844/4885HTR2C 3755/4885 |
| US-20150080582-A1 | OPTICAL FILM, RETARDATION PLATE, ELLIPTICA POLARIZING PLATE, LIQUID CRYSTAL DISPLAY DEVICE AND COMPOUND | PYM1, CCND2, CCNB2 | NAAA 4611/4885DGKA 4882/4885HTR2C 551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.