Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 3/20 | 0.52 |
| ▸ | ITGB7 | P26010 | 3/20 | 0.52 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 2/20 | 0.47 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 6/20 | 0.43 |
| ▸ | PPARG | P37231 | 5/20 | 0.43 |
| ▸ | CTSS | P25774 | 4/20 | 0.43 |
| ▸ | CTSK | P43235 | 4/20 | 0.43 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25222740 | 1.00 | ITGA4 (0.52) | ITGA4ITGB7ITGB3ITGA2BACE | |
| SCHEMBL30461939 | 1.00 | ITGA4 (0.52) | ITGA4ITGB7ITGB3ITGA2BACE | |
| SCHEMBL31407717 | 1.00 | ITGA4 (0.52) | ITGA4ITGB7ITGB3ITGA2BACE | |
| SCHEMBL25216220 | 0.91 | ITGA4 (0.52) | ITGA4ITGB7ITGB3ITGA2BACE | |
| SCHEMBL25268681 | 0.91 | ITGA4 (0.52) | ITGA4ITGB7ITGB3ITGA2BACE | |
| SCHEMBL30461882 | 0.91 | TACR1 (0.51) | ITGA4ITGB7TACR1SCN9ACTSS | |
| SCHEMBL3376451 | 0.83 | TACR1 (0.60) | ITGA4ITGB7ITGB3ITGA2BACE | |
| SCHEMBL3376442 | 0.83 | TACR1 (0.60) | ITGA4ITGB7ITGB3ITGA2BACE | |
| SCHEMBL31407351 | 0.83 | TACR1 (0.60) | ITGA4ITGB7ITGB3ITGA2BACE | |
| SCHEMBL25216680 | 0.82 | ACE (0.47) | ITGA4ITGB7ITGB3ITGA2BACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107597-A2 | BICYCLIC HETEROAROMATIC AMIDE COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |