Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.43 |
| ▸ | ITGB7 | P26010 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 7/20 | 0.40 |
| ▸ | CTSK | P43235 | 6/20 | 0.40 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.39 |
| ▸ | GSTM2 | P28161 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 3/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30461878 | 0.91 | TACR1 (0.48) | TACR1CACNA1BKLK5ITGA4ITGB7 | |
| SCHEMBL31407717 | 0.91 | ITGA4 (0.52) | TACR1CACNA1BITGA4ITGB7CTSS | |
| SCHEMBL25222740 | 0.91 | ITGA4 (0.52) | TACR1CACNA1BITGA4ITGB7CTSS | |
| SCHEMBL25262301 | 0.91 | ITGA4 (0.52) | TACR1CACNA1BITGA4ITGB7CTSS | |
| SCHEMBL30461939 | 0.91 | ITGA4 (0.52) | TACR1CACNA1BITGA4ITGB7CTSS | |
| SCHEMBL4069829 | 0.85 | KLK5 (0.43) | TACR1KLK5CTSSCTSKGSTP1 | |
| SCHEMBL31494632 | 0.84 | CTSS (0.49) | TACR1KLK5CTSSCTSKGSTP1 | |
| SCHEMBL30461868 | 0.84 | KLK5 (0.43) | TACR1CACNA1BKLK5CTSSCTSK | |
| SCHEMBL30461885 | 0.84 | KLK5 (0.43) | TACR1CACNA1BKLK5CTSSCTSK | |
| SCHEMBL25268681 | 0.81 | ITGA4 (0.52) | TACR1ITGA4ITGB7CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107597-A2 | BICYCLIC HETEROAROMATIC AMIDE COMPOUNDS AND USES THEREOF | Kineta, Inc. (US) | 2023-06-15 | — | — | WO | disclosed |