Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PARL | Q9H300 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL133554 | 0.86 | KMT2A (0.53) | KMT2AMGLLF2LMNAMAPK1 | |
| SCHEMBL19309377 | 0.86 | KMT2A (0.53) | KMT2AMGLLF2LMNAMAPK1 | |
| SCHEMBL915835 | 0.81 | TDP1 (0.44) | KMT2AMGLLF2LMNAMAPK1 | |
| SCHEMBL3106205 | 0.81 | TDP1 (0.51) | KMT2AMGLLLMNAMAPK1MAPT | |
| SCHEMBL76714 | 0.80 | KMT2A (0.48) | KMT2AMGLLF2LMNAMAPK1 | |
| SCHEMBL15169077 | 0.80 | KMT2A (0.48) | KMT2AMGLLF2LMNAMAPK1 | |
| SCHEMBL15169078 | 0.80 | KMT2A (0.48) | KMT2AMGLLF2LMNAMAPK1 | |
| Hydrogen Peroxide SCHEMBL28931710 | 0.80 | LMNA (0.64) | KMT2AF2LMNAMAPK1TSHR | |
| SCHEMBL7589769 | 0.80 | LMNA (0.64) | KMT2AF2LMNAMAPK1TSHR | |
| SCHEMBL4702445 | 0.79 | TDP1 (0.57) | KMT2AMGLLLMNAMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981903-B1 | ASPARAGINE-10-SUBSTITUTED NONADEPSIPEPTIDES | AICURIS GMBH & CO KG (DE) | 2009-10-21 | — | — | EP | disclosed |
| EP-1981903-A1 | ASPARAGINE-10-SUBSTITUTED NONADEPSIPEPTIDES | AiCuris GmbH & Co. KG (DE) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007085456-A1 | ASPARAGINE-10-SUBSTITUTED NONADEPSIPEPTIDES | AICURIS GMBH & CO. KG (DE) | 2007-08-02 | — | — | WO | disclosed |
| WO-2003062232-A1 | DERIVATIVES OF THIAZOLES USED FOR THE TREATMENT OF NEUROLOGICAL DISEASES | SOCIETE DE CONSEILS DE RECHERCHE ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2003-07-31 | — | — | WO | disclosed |