SCHEMBL25201348

SCHEMBL25201348

Cn1ccn(Cc2cc(Br)c3c(c2)C(=O)CCO3)/c1=N\C(=O)O

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 0.30
CYP2D6 P10635 1/20 0.30
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25201351 1.00 HTR1A (0.30) HTR1ACYP2D6SLC6A4
SCHEMBL30427510 0.87 GPR119 (0.32) HTR1ACYP2D6SLC6A4
SCHEMBL22750301 0.85 ACLY (0.33)
SCHEMBL22750300 0.85 ACLY (0.33)
SCHEMBL30427520 0.85 MEN1 (0.31) HTR1ACYP2D6SLC6A4
SCHEMBL25186862 0.84 WDR5 (0.37)
SCHEMBL25264769 0.84 WDR5 (0.37)
SCHEMBL25189659 0.82 WDR5 (0.49)
SCHEMBL25195647 0.81 WDR5 (0.43)
SCHEMBL30427932 0.81 WDR5 (0.43)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023090829-A1 LOW-MOLECULAR-WEIGHT COMPOUND FOR REGULATING MLL1-WDR5 INTERACTION AND USE THEREOF 엘젠테라퓨틱스 주식회사 2023-05-25 WO disclosed