Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 4/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.42 |
| ▸ | KLK7 | P49862 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25208230 | 1.00 | HDAC8 (0.43) | HDAC8HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL25364561 | 0.91 | SIRT1 (0.41) | HDAC8HDAC1HDAC2HDAC3HDAC10 | |
| SCHEMBL25364554 | 0.91 | SIRT1 (0.41) | HDAC8HDAC1HDAC2HDAC3HDAC10 | |
| SCHEMBL12683176 | 0.89 | HDAC8 (0.44) | HDAC8HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL12476216 | 0.89 | HDAC8 (0.44) | HDAC8HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL12476215 | 0.89 | HDAC8 (0.44) | HDAC8HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL18388780 | 0.87 | LTA4H (0.48) | HDAC8HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL25223009 | 0.87 | LTA4H (0.48) | HDAC8HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL16847584 | 0.86 | HDAC8 (0.57) | HDAC8HDAC1HDAC2HDAC3HDAC4 | |
| SCHEMBL15702053 | 0.85 | USP30 (0.42) | HDAC8HDAC1HDAC2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230270867-A1 | CONJUGATE IN WHICH FL118 DRUG IS LINKED TO ACID-SENSITIVE LINKER, AND IMMUNOCONJUGATE USING SAME | PINOTBIO, INC. (KR) | 2023-08-31 | — | — | US | disclosed |
| EP-4183418-A1 | CONJUGATE IN WHICH FL118 DRUG IS LINKED TO ACID-SENSITIVE LINKER, AND IMMUNOCONJUGATE USING SAME | Pinotbio, Inc. (KR) | 2023-05-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230270867-A1 | CONJUGATE IN WHICH FL118 DRUG IS LINKED TO ACID-SENSITIVE LINKER, AND IMMUNOCONJUGATE USING SAME | SLC46A1, SLC47A1, FOLR1 | HDAC8 1121/4885HDAC1 3656/4885HDAC2 4225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.