Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.35 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9292311 | 1.00 | CYP2C19 (0.50) | CYP2C19SMN1; SMN2TRPA1ALDH1A1KDM4E | |
| SCHEMBL28548984 | 0.89 | CYP2C19 (0.47) | CYP2C19SMN1; SMN2TRPA1ALDH1A1KDM4E | |
| SCHEMBL7092137 | 0.87 | CYP2C19 (0.46) | CYP2C19SMN1; SMN2TRPA1ALDH1A1KDM4E | |
| SCHEMBL8059298 | 0.84 | CYP2C19 (0.53) | CYP2C19SMN1; SMN2TRPA1ALDH1A1KDM4E | |
| SCHEMBL5161045 | 0.84 | CYP2C19 (0.53) | CYP2C19SMN1; SMN2TRPA1ALDH1A1KDM4E | |
| SCHEMBL19285367 | 0.84 | CYP2C19 (0.53) | CYP2C19SMN1; SMN2TRPA1ALDH1A1KDM4E | |
| SCHEMBL9003499 | 0.83 | CYP2C19 (0.55) | CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL1308070 | 0.81 | TRPA1 (0.52) | SMN1; SMN2TRPA1ALDH1A1KDM4EGABBR2 | |
| SCHEMBL11364164 | 0.81 | HRH1 (0.52) | CYP2C19SMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL9254662 | 0.81 | TRPA1 (0.42) | CYP2C19SMN1; SMN2TRPA1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088955-B2 | Alpha-substituted α,β-unsaturated E- or Z-aldehydes, use thereof, and processes for their preparation α,β | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO. KG (AT) | 2012-01-03 | — | — | US | disclosed |
| US-20110301365-A1 | ALPHA-SUBSTITUTED ALPHA, BETA-UNSATURATED E- OR Z-ALDEHYDES, USE THEREOF, AND PROCESSES FOR THEIR PREPARATION ALPHA, BETA | DSM IP ASSETS B.V. (NL) | 2011-12-08 | — | — | US | disclosed |
| US-20100234630-A1 | ALPHA-SUBSTITUTED A,B-UNSATURATED E- OR Z-ALDEHYDES, USE THEREOF, AND PROCESSES FOR THEIR PREPARATION A,B | DSM FINE CHEMICALS AUSTRIA NFG GMBH & COKG (AT) | 2010-09-16 | — | — | US | disclosed |
| EP-2178816-A1 | ALPHA-SUBSTITUTED , -UNSATURATED E- OR Z-ALDEHYDES, USE THEREOF, AND PROCESSES FOR THEIR PREPARATION , | DSM Fine Chemicals Austria Nfg GmbH & Co KG (AT) | 2010-04-28 | — | — | EP | disclosed |
| WO-2009007462-A1 | ALPHA-SUBSTITUTED α,β-UNSATURATED E- OR Z-ALDEHYDES, USE THEREOF, AND PROCESSES FOR THEIR PREPARATION α,β | DSM FINE CHEMICALS AUSTRIA NFG GMBH & CO. KG (AT) | 2009-01-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301365-A1 | ALPHA-SUBSTITUTED ALPHA, BETA-UNSATURATED E- OR Z-ALDEHYDES, USE THEREOF, AND PROCESSES FOR THEIR PREPARATION ALPHA, BETA | CYP8B1, ECH1, NR1H2 | CYP2C19 291/4885SMN1; SMN2 2976/4885TRPA1 1077/4885 |
| US-20100234630-A1 | ALPHA-SUBSTITUTED A,B-UNSATURATED E- OR Z-ALDEHYDES, USE THEREOF, AND PROCESSES FOR THEIR PREPARATION A,B | CYP8B1, CYP1B1, ADRA1A | CYP2C19 169/4885SMN1; SMN2 2920/4885TRPA1 1130/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.