Hydrochloric Acid

Hydrochloric Acid

SCHEMBL252691

C=Cc1cc[n+](CC(=O)O)cc1.[Cl-]

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
ACHE known ✓ P22303 3/20 0.38
HDAC8 Q9BY41 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.39
ALDH1A1 P00352 4/20 0.38
TSHR P16473 1/20 0.38
LMNA P02545 2/20 0.36
RAB9A P51151 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
POLB P06746 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
HSP90AA1 P07900 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4195194 0.98 HDAC8 (0.43) HDAC8SMN1; SMN2ACHEALDH1A1TSHR
Betaine SCHEMBL4654474 0.85 TSHR (0.42) HDAC8SMN1; SMN2ACHEALDH1A1TSHR
Hydrochloric Acid SCHEMBL6112322 0.81 HDAC8 (0.39) HDAC8SMN1; SMN2ACHEALDH1A1TSHR
SCHEMBL21291698 0.81 HDAC8 (0.42) HDAC8SMN1; SMN2ACHEALDH1A1TSHR
Bromide SCHEMBL16322851 0.79 HDAC8 (0.41) HDAC8SMN1; SMN2ACHEALDH1A1TSHR
Hydrochloric Acid SCHEMBL2864557 0.77 KDM4E (0.44) SMN1; SMN2ACHEALDH1A1LMNARAB9A
SCHEMBL16983793 0.76 ALDH1A1 (0.60) SMN1; SMN2ACHEALDH1A1LMNAMEN1
SCHEMBL11227570 0.74 KDM4E (0.46) SMN1; SMN2ALDH1A1TSHRLMNARAB9A
SCHEMBL10880403 0.74 HDAC8 (0.48) HDAC8SMN1; SMN2ACHEALDH1A1TSHR
SCHEMBL20840124 0.74 HDAC8 (0.56) HDAC8SMN1; SMN2ACHEALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4402236-A1 LAUNDRY COMPOSITION FOR THE REMOVAL OF STAINS Reckitt Benckiser Vanish B.V. (NL) 2024-07-24 EP claimed
WO-2023041739-A1 LAUNDRY COMPOSITION FOR THE REMOVAL OF STAINS RECKITT BENCKISER VANISH B.V. (NL) 2023-03-23 WO claimed
WO-2022271898-A1 COLOUR CARE DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2022-12-29 WO claimed
US-20220411722-A1 COLOUR CARE DETERGENT COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2022-12-29 US claimed
EP-4108749-A1 COLOUR CARE DETERGENT COMPOSITIONS The Procter & Gamble Company (US) 2022-12-28 EP claimed
US-11214761-B2 Solid perfume composition delivering fabric care Henkel IP & Holding GmbH (DE) 2022-01-04 US claimed
US-20210198601-A1 Solid Perfume Composition Delivering Fabric Care Henkel IP & Holding GmbH (DE) 2021-07-01 US claimed
WO-2021115741-A1 IMPROVED DETERGENT POWER OF COLOR DETERGENTS ON BLEACHABLE STAINS, PRESERVING COLOR HENKEL AG & CO. KGAA (DE) 2021-06-17 WO claimed
US-10457894-B2 Color-protecting detergent or cleaning agent having an optical brightener HENKEL AG & CO. KGAA (DE) 2019-10-29 US claimed
EP-2976415-B1 COLOUR PROTECTING DETERGENT COMPOPOSITION COMPRISING AN OPTICAL BRIGHTENER HENKEL AG & CO KGAA (DE) 2018-10-17 EP claimed
US-20160010030-A1 COLOR-PROTECTING DETERGENT OR CLEANING AGENT HAVING AN OPTICAL BRIGHTENER HENKEL AG & CO. KGAA (DE) 2016-01-14 US claimed
EP-2176392-B1 COLOR-SAFE DETERGENT OR CLEANING AGENT HAVING OPTICAL BRIGHTENER HENKEL AG & CO KGAA (DE) 2013-10-23 EP claimed
US-20100144579-A1 Color-Safe Detergent or Cleaning Agent having Optical Brightener HENKEL AG & CO. KGAA (DE) 2010-06-10 US claimed
US-20090029898-A1 Washing or Cleaning Composition Comprising Dye Transfer Inhibitor HENKEL AG & CO. KGAA (DE) 2009-01-29 US claimed
EP-4402236-A1 LAUNDRY COMPOSITION FOR THE REMOVAL OF STAINS Reckitt Benckiser Vanish B.V. (NL) 2024-07-24 EP disclosed
EP-4402236-A1 LAUNDRY COMPOSITION FOR THE REMOVAL OF STAINS Reckitt Benckiser Vanish B.V. (NL) 2024-07-24 EP disclosed
US-20240240115-A1 COMPOSITION WITH IMPROVED MOISTURE MANAGEMENT PERFORMANCE HENKEL AG & CO. KGAA (DE) 2024-07-18 US disclosed
WO-2003014277-A1 IMPROVEMENTS RELATING TO COLOUR-SAFE FABRIC TREATMENT COMPOSITIONS UNILEVER PLC (GB) 2003-02-20 WO disclosed
WO-2003014280-A1 BLEACHING COMPOSITIONS UNILEVER PLC (GB) 2003-02-20 WO disclosed
US-20020112294-A1 Dye fixing composition Henkel IP & Holding GmbH (DE) 2002-08-22 US disclosed