Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11227570 | 0.98 | KDM4E (0.46) | KDM4EALDH1A1HTTSMN1; SMN2MITF | |
| SCHEMBL29019022 | 0.90 | MEN1 (0.46) | KDM4EALDH1A1HTTSMN1; SMN2MITF | |
| SCHEMBL16843093 | 0.87 | SLC6A4 (0.50) | KDM4EALDH1A1HTTSMN1; SMN2MITF | |
| SCHEMBL22340639 | 0.84 | WNT3A (0.40) | KDM4EALDH1A1HTTSMN1; SMN2MITF | |
| SCHEMBL22340400 | 0.82 | MEN1 (0.44) | KDM4EALDH1A1HTTSMN1; SMN2MITF | |
| SCHEMBL20414476 | 0.80 | KDM4E (0.35) | KDM4EALDH1A1HTTSMN1; SMN2MITF | |
| SCHEMBL4258978 | 0.79 | HTT (0.45) | KDM4EALDH1A1HTTSMN1; SMN2MAPT | |
| Hydrochloric Acid SCHEMBL9250120 | 0.79 | HTT (0.42) | KDM4EALDH1A1HTTSMN1; SMN2MITF | |
| Hydrochloric Acid SCHEMBL8960715 | 0.79 | FFAR1 (0.41) | KDM4EALDH1A1HTTSMN1; SMN2MITF | |
| SCHEMBL11001188 | 0.79 | RAB9A (0.39) | KDM4EALDH1A1HTTSMN1; SMN2MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2098582-B1 | FUNCTIONAL ELECTRODE AND FUNCTIONAL ELECTROCHROMIC DEVICE | RICOH CO LTD (JP) | 2017-12-06 | — | — | EP | disclosed |
| US-7830584-B2 | Organic-inorganic composite material and method for producing the same, and functional electrode and functional device | RICOH COMPANY, LTD. (JP) | 2010-11-09 | — | — | US | disclosed |
| EP-2098582-A1 | ORGANIC INORGANIC COMPOSITE MATERIAL, PROCESS FOR PRODUCING THE SAME, AND FUNCTIONAL ELECTRODE AND FUNCTIONAL DEVICE | Ricoh Company, Ltd. (JP) | 2009-09-09 | — | — | EP | disclosed |
| US-20090002802-A1 | ORGANIC-INORGANIC COMPOSITE MATERIAL AND METHOD FOR PRODUCING THE SAME, AND FUNCTIONAL ELECTRODE AND FUNCTIONAL DEVICE | RICOH COMPANY, LTD. (JP) | 2009-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090002802-A1 | ORGANIC-INORGANIC COMPOSITE MATERIAL AND METHOD FOR PRODUCING THE SAME, AND FUNCTIONAL ELECTRODE AND FUNCTIONAL DEVICE | EPCAM, ILK, L1CAM | ACHE 605/4885KDM4E 2183/4885ALDH1A1 992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.