Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 5/20 | 0.80 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.75 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.68 |
| ▸ | MCOLN3 | Q8TDD5 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5246679 | 0.89 | AKR1C3 (1.00) | AKR1C3EIF2AK3AKR1C1MCOLN3TSHR | |
| SCHEMBL7312299 | 0.85 | AKR1C3 (0.93) | AKR1C3EIF2AK3AKR1C1MCOLN3TSHR | |
| SCHEMBL22191886 | 0.85 | AKR1C3 (1.00) | AKR1C3EIF2AK3AKR1C1MCOLN3TSHR | |
| SCHEMBL28983197 | 0.85 | AKR1C3 (0.70) | AKR1C3EIF2AK3AKR1C1MCOLN3TSHR | |
| SCHEMBL21670262 | 0.84 | LMNA (0.70) | AKR1C3AKR1C1TSHRLMNAALDH1A1 | |
| SCHEMBL5244699 | 0.83 | EIF2AK3 (0.74) | AKR1C3EIF2AK3AKR1C1TSHRALDH1A1 | |
| SCHEMBL6791608 | 0.82 | CYP2C19 (0.76) | AKR1C3EIF2AK3TSHRALDH1A1KMT2A | |
| SCHEMBL7304595 | 0.81 | AKR1C3 (0.82) | AKR1C3EIF2AK3AKR1C1MCOLN3TSHR | |
| SCHEMBL610187 | 0.81 | EIF2AK3 (0.72) | AKR1C3EIF2AK3AKR1C1MCOLN3TSHR | |
| SCHEMBL610186 | 0.81 | EIF2AK3 (0.72) | AKR1C3EIF2AK3AKR1C1MCOLN3TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4192816-A1 | COMPOUNDS AS C5AR INHIBITORS | Kira Pharmaceuticals (Suzhou) Ltd. (CN) | 2023-06-14 | — | — | EP | disclosed |