Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 11/20 | 0.35 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.35 |
| ▸ | PARP6 | Q2NL67 | 2/20 | 0.35 |
| ▸ | PARP3 | Q9Y6F1 | 2/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | IKZF2 | Q9UKS7 | 4/20 | 0.34 |
| ▸ | MAOA | P21397 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25235773 | 0.84 | CRBN (0.44) | CRBNIKZF3PARP1PARP2PARP6 | |
| SCHEMBL30459674 | 0.82 | HTR2B (0.39) | CRBNIKZF3PARP1PARP2PARP6 | |
| SCHEMBL25422652 | 0.82 | HTR2A (0.38) | CRBNIKZF3PARP1PARP2IKZF2 | |
| SCHEMBL25420240 | 0.81 | PARP1 (0.39) | CRBNIKZF3PARP1PARP2IKZF2 | |
| SCHEMBL27036816 | 0.80 | MAOA (0.37) | CRBNIKZF2MAOA | |
| SCHEMBL25422666 | 0.79 | MAOA (0.35) | CRBNIKZF3PARP1PARP2KCNH2 | |
| SCHEMBL25422761 | 0.79 | MAOA (0.35) | CRBNIKZF3PARP1PARP2KCNH2 | |
| Hydrochloric Acid SCHEMBL29099257 | 0.78 | MAOA (0.41) | CRBNIKZF3PARP1KCNH2MAOA | |
| SCHEMBL25421720 | 0.77 | HTR2A (0.39) | CRBNIKZF3PARP1PARP2KCNH2 | |
| SCHEMBL31076678 | 0.77 | IKZF2 (0.57) | CRBNIKZF3IKZF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | claimed |