Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 4/20 | 0.39 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | PARP1 | P09874 | 7/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.36 |
| ▸ | IKZF2 | Q9UKS7 | 5/20 | 0.36 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.35 |
| ▸ | TNK1 | Q13470 | 1/20 | 0.35 |
| ▸ | WIZ | O95785 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.34 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | TNKS | O95271 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26110172 | 0.83 | IKZF2 (0.52) | HTR2BHTR2AHTR2CPARP1IKZF2 | |
| SCHEMBL25270702 | 0.82 | CRBN (0.38) | PARP1CRBNIKZF3IKZF2TNKS | |
| SCHEMBL30790468 | 0.82 | HTR2C (0.51) | HTR2BHTR2AHTR2CPARP1IKZF2 | |
| SCHEMBL30458487 | 0.82 | CRBN (0.42) | HTR2BHTR2AHTR2CPARP1CRBN | |
| SCHEMBL30459017 | 0.81 | HTR2C (0.46) | HTR2BHTR2AHTR2CPARP1IKZF2 | |
| SCHEMBL31076678 | 0.80 | IKZF2 (0.57) | CRBNIKZF3IKZF2WIZ | |
| SCHEMBL25647405 | 0.80 | IKZF2 (0.57) | CRBNIKZF3IKZF2WIZ | |
| SCHEMBL30458859 | 0.79 | PARP1 (0.46) | HTR2BHTR2AHTR2CPARP1TNK2 | |
| SCHEMBL30741716 | 0.78 | PARP1 (0.42) | HTR2BHTR2AHTR2CPARP1CRBN | |
| SCHEMBL30458379 | 0.76 | HTR2B (0.44) | HTR2BHTR2AHTR2CPARP1IKZF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023104155-A1 | LIGAND COMPOUNDS FOR E3 UBIQUITIN LIGASE, PROTEIN DEGRADERS DEVELOPED ON BASIS OF LIGAND COMPOUNDS, AND USES THEREOF | 标新生物医药科技(上海)有限公司 | 2023-06-15 | — | — | WO | claimed |