Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GRK6 | P43250 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25226274 | 0.90 | ESR2 (0.52) | BACE1HDAC4HDAC2HDAC8ACLY | |
| SCHEMBL13251023 | 0.86 | ABL1 (0.52) | GAAPOLBGRK6BLMGFER | |
| SCHEMBL25271592 | 0.85 | ABL1 (0.42) | GAAPOLBGRK6BLMGFER | |
| SCHEMBL13251065 | 0.80 | ACACA (0.59) | BACE1SMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL25223726 | 0.79 | CNR1 (0.40) | NOD2SMN1; SMN2TP53NPC1RAB9A | |
| SCHEMBL15945801 | 0.79 | NOD2 (0.43) | GAAPOLBGRK6BLMGFER | |
| SCHEMBL13251086 | 0.78 | NPC1 (0.49) | NOD2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL13250973 | 0.78 | NPC1 (0.49) | NOD2NPC1RAB9AMEN1KMT2A | |
| SCHEMBL29227269 | 0.77 | IDO1 (0.38) | BACE1HDAC4HDAC2HDAC8ACLY | |
| SCHEMBL13251058 | 0.75 | ACACA (0.44) | GAAPOLBGRK6BLMGFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023103611-A1 | BROMOPYRENE INTERMEDIATE AND DERIVATIVES THEREOF, PREPARATION METHOD, AND USE | 广东工业大学 | 2023-06-15 | — | — | WO | disclosed |
| WO-2023103611-A1 | BROMOPYRENE INTERMEDIATE AND DERIVATIVES THEREOF, PREPARATION METHOD, AND USE | 广东工业大学 | 2023-06-15 | — | — | WO | disclosed |
| CN-114149307-B | Bromopyrene intermediate and derivative, preparation method and application thereof | 广东工业大学 | 2023-04-11 | — | — | CN | disclosed |
| CN-114149307-A | Bromopyrene intermediate and derivative, preparation method and application thereof | 广东工业大学 | 2022-03-08 | — | — | CN | disclosed |