Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | BCR | P11274 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25224619 | 0.91 | KDM4E (0.43) | CNR1CNR2GPR35GPR55RAB9A | |
| SCHEMBL25271592 | 0.86 | ABL1 (0.42) | MAPTALDH1A1SMN1; SMN2ABL1ABCB1 | |
| SCHEMBL25225360 | 0.83 | MGAM (0.49) | LMNAHTTMAPTALDH1A1ACACA | |
| SCHEMBL13251023 | 0.81 | ABL1 (0.52) | RAB9ATP53KDM4EHPGDALDH1A1 | |
| SCHEMBL25271741 | 0.79 | GAA (0.48) | LMNARAB9ATP53KDM4EHPGD | |
| SCHEMBL14498830 | 0.77 | ABL1 (0.51) | TDP1LMNAHTTADORA3KDM4E | |
| SCHEMBL25272516 | 0.76 | CA1 (0.46) | RAB9ATP53KDM4EMAPTNPC1 | |
| SCHEMBL13251065 | 0.75 | ACACA (0.59) | TDP1LMNAHTTRAB9ATP53 | |
| SCHEMBL15945801 | 0.74 | NOD2 (0.43) | LMNARAB9ATP53KDM4EHPGD | |
| SCHEMBL28713191 | 0.74 | ADORA3 (0.37) | TDP1LMNAHTTADORA3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023103611-A1 | BROMOPYRENE INTERMEDIATE AND DERIVATIVES THEREOF, PREPARATION METHOD, AND USE | 广东工业大学 | 2023-06-15 | — | — | WO | disclosed |
| WO-2023103611-A1 | BROMOPYRENE INTERMEDIATE AND DERIVATIVES THEREOF, PREPARATION METHOD, AND USE | 广东工业大学 | 2023-06-15 | — | — | WO | disclosed |
| CN-114149307-B | Bromopyrene intermediate and derivative, preparation method and application thereof | 广东工业大学 | 2023-04-11 | — | — | CN | disclosed |
| CN-114149307-A | Bromopyrene intermediate and derivative, preparation method and application thereof | 广东工业大学 | 2022-03-08 | — | — | CN | disclosed |