Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 5/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.36 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ATR | Q13535 | 1/20 | 0.35 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31052395 | 1.00 | L3MBTL1 (0.48) | L3MBTL1BRD4HTR6PKMALDH1A1 | |
| SCHEMBL32667896 | 0.88 | SMN1; SMN2 (0.46) | L3MBTL1BRD4PKMALDH1A1HTT | |
| SCHEMBL15426836 | 0.85 | L3MBTL1 (0.53) | L3MBTL1BRD4HTR6PKMALDH1A1 | |
| SCHEMBL1015374 | 0.84 | L3MBTL1 (0.52) | L3MBTL1BRD4HTR6PKMALDH1A1 | |
| SCHEMBL4724390 | 0.83 | L3MBTL1 (0.51) | L3MBTL1BRD4HTR6PKMALDH1A1 | |
| SCHEMBL4793803 | 0.82 | L3MBTL1 (0.50) | L3MBTL1BRD4HTR6PKMALDH1A1 | |
| SCHEMBL31246107 | 0.82 | L3MBTL1 (0.50) | L3MBTL1BRD4HTR6PKMALDH1A1 | |
| SCHEMBL31052234 | 0.82 | L3MBTL1 (0.45) | L3MBTL1BRD4HTR6RAPGEF4CA1 | |
| SCHEMBL25273851 | 0.82 | L3MBTL1 (0.45) | L3MBTL1BRD4HTR6RAPGEF4CA1 | |
| SCHEMBL31052307 | 0.82 | L3MBTL1 (0.45) | L3MBTL1BRD4HTR6PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023103898-A1 | COMPOUND HAVING CLK AND DYRK INHIBITORY ACTIVITIES, PREPARATION METHOD THEREFOR AND USE THEREOF | 赛诺哈勃药业（成都）有限公司 | 2023-06-15 | — | — | WO | disclosed |