Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 5/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 3/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | UBE2N | P61088 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.34 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25216328 | 1.00 | L3MBTL1 (0.45) | L3MBTL1HTR6BRD4PKMRAPGEF4 | |
| SCHEMBL25273685 | 0.82 | L3MBTL1 (0.48) | L3MBTL1HTR6BRD4PKMRAPGEF4 | |
| SCHEMBL31052395 | 0.82 | L3MBTL1 (0.48) | L3MBTL1HTR6BRD4PKMRAPGEF4 | |
| SCHEMBL25220975 | 0.82 | RAPGEF4 (0.38) | L3MBTL1HTR6RAPGEF4HDAC1ALDH1A1 | |
| SCHEMBL25273851 | 0.79 | L3MBTL1 (0.45) | L3MBTL1HTR6BRD4RAPGEF4CA1 | |
| SCHEMBL31052234 | 0.79 | L3MBTL1 (0.45) | L3MBTL1HTR6BRD4RAPGEF4CA1 | |
| SCHEMBL30542311 | 0.79 | L3MBTL1 (0.36) | L3MBTL1BRD4RAPGEF4KDM4EUBE2N | |
| SCHEMBL31052300 | 0.78 | L3MBTL1 (0.44) | L3MBTL1HTR6BRD4PKMRAPGEF4 | |
| SCHEMBL16809588 | 0.78 | L3MBTL1 (0.49) | L3MBTL1HTR6BRD4PKMRAPGEF4 | |
| SCHEMBL25220806 | 0.77 | L3MBTL1 (0.44) | L3MBTL1HTR6BRD4RAPGEF4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118525020-A | Compound with CLK and DYRK inhibiting activity, preparation method and application thereof | 赛诺哈勃药业（成都）有限公司 | 2024-08-20 | — | — | CN | disclosed |