Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 11/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 9/20 | 0.35 |
| ▸ | HPGD | P15428 | 6/20 | 0.35 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 6/20 | 0.35 |
| ▸ | USP2 | O75604 | 6/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25422458 | 0.86 | ALDH1A1 (0.35) | HSD17B10ALDH1A1CYP3A4HPGDTSHR | |
| SCHEMBL31579068 | 0.86 | MAP4K4 (0.43) | HSD17B10ALDH1A1CYP3A4CYP2C19USP2 | |
| SCHEMBL25423715 | 0.85 | MEN1 (0.38) | HSD17B10ALDH1A1CYP3A4HPGDTSHR | |
| SCHEMBL30406184 | 0.82 | OPRD1 (0.38) | HSD17B10ALDH1A1CYP3A4TSHRSMN1; SMN2 | |
| SCHEMBL25724531 | 0.81 | AKT1 (0.41) | AKT1HSD17B10ALDH1A1CYP3A4HPGD | |
| SCHEMBL25281197 | 0.78 | HTT (0.53) | AKT1ALDH1A1HPGDMAPK1USP2 | |
| SCHEMBL30406387 | 0.78 | HTT (0.53) | AKT1ALDH1A1HPGDMAPK1USP2 | |
| SCHEMBL31578990 | 0.75 | MAP4K4 (0.42) | HSD17B10ALDH1A1CYP3A4CYP2C19USP2 | |
| SCHEMBL25272457 | 0.75 | AKT1 (0.49) | AKT1HSD17B10ALDH1A1CYP3A4HPGD | |
| SCHEMBL25724551 | 0.74 | MAP4K4 (0.41) | HSD17B10ALDH1A1CYP3A4CYP2C19USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |