Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 10/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.35 |
| ▸ | USP2 | O75604 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25231891 | 0.83 | AKT1 (0.38) | AKT1ALDH1A1HSD17B10HPGDCYP1A2 | |
| SCHEMBL25274640 | 0.81 | AKT1 (0.36) | AKT1ALDH1A1HSD17B10HPGDCYP1A2 | |
| SCHEMBL31579068 | 0.76 | MAP4K4 (0.43) | ALDH1A1HSD17B10CYP2D6USP2CYP3A4 | |
| SCHEMBL30406184 | 0.72 | OPRD1 (0.38) | ALDH1A1HSD17B10HTTTSHRCYP2D6 | |
| SCHEMBL25273633 | 0.71 | ALDH1A1 (0.51) | AKT1ALDH1A1HSD17B10HPGDCYP1A2 | |
| SCHEMBL25272447 | 0.71 | ALDH1A1 (0.37) | AKT1ALDH1A1HSD17B10HPGDCYP1A2 | |
| SCHEMBL25277572 | 0.71 | HTT (0.44) | AKT1ALDH1A1HSD17B10HPGDCYP1A2 | |
| SCHEMBL25275560 | 0.70 | PIM1 (0.48) | ALDH1A1HSD17B10HPGDCYP1A2HTT | |
| SCHEMBL30455740 | 0.70 | HTT (0.44) | ALDH1A1HSD17B10HPGDCYP1A2HTT | |
| SCHEMBL25222339 | 0.70 | HTT (0.44) | ALDH1A1HSD17B10HPGDCYP1A2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023107696-A2 | INHIBITORS OF MENIN-MLL INTERACTION | BALA THERAPEUTICS, INC. (US) | 2023-06-15 | — | — | WO | disclosed |