Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 1/20 | 0.45 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.35 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25231435 | 0.91 | GRIA2 (0.45) | GRIA2NPY5RMALT1SCN9APTGS2 | |
| SCHEMBL30469088 | 0.91 | GRIA2 (0.45) | GRIA2NPY5RMALT1SCN9APTGS2 | |
| SCHEMBL25281888 | 0.88 | GRIA2 (0.45) | GRIA2NPY5RMALT1SCN9ASYK | |
| SCHEMBL30469100 | 0.88 | GRIA2 (0.45) | GRIA2NPY5RMALT1SCN9ASYK | |
| SCHEMBL25280726 | 0.85 | KHK (0.41) | GRIA2NPY5RSCN9APTGS2 | |
| SCHEMBL25239870 | 0.84 | PTGS2 (0.44) | GRIA2NPY5RMALT1SCN9APTGS2 | |
| SCHEMBL25276440 | 0.81 | GRIA2 (0.45) | GRIA2MALT1SCN9ACYP2C9CNR1 | |
| SCHEMBL25239918 | 0.80 | SCN9A (0.46) | GRIA2NPY5RSCN9APTGS2EPHX2 | |
| SCHEMBL30469106 | 0.80 | SCN9A (0.46) | GRIA2NPY5RSCN9APTGS2EPHX2 | |
| SCHEMBL25230406 | 0.80 | NPY5R (0.41) | GRIA2NPY5RSCN9ASYKPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230202985-A1 | Indoles, Indazoles, and Related Analogs for Inhibiting YAP/TAZ-TEAD | CISTIM LEUVEN VZW (BE) | 2023-06-29 | — | — | US | disclosed |
| US-20230202985-A1 | Indoles, Indazoles, and Related Analogs for Inhibiting YAP/TAZ-TEAD | CISTIM LEUVEN VZW (BE) | 2023-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230202985-A1 | Indoles, Indazoles, and Related Analogs for Inhibiting YAP/TAZ-TEAD | YAP1, TEAD2, TEAD3 | GRIA2 3796/4885NPY5R 2669/4885MALT1 1280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.