Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 6/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.46 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.46 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.45 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 9/20 | 0.43 |
| ▸ | JAK1 | P23458 | 8/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2632955 | 0.83 | NUDT1 (0.50) | AXLNUDT1MAP2K1TTBK1TTBK2 | |
| SCHEMBL31403755 | 0.83 | NUDT1 (0.50) | AXLNUDT1MAP2K1TTBK1TTBK2 | |
| SCHEMBL30985188 | 0.82 | AXL (0.55) | AXLNUDT1MAP2K1TTBK1TTBK2 | |
| SCHEMBL21632535 | 0.82 | JAK3 (0.46) | AXLNUDT1MAP2K1TTBK1TTBK2 | |
| SCHEMBL31403683 | 0.82 | JAK3 (0.46) | AXLNUDT1MAP2K1TTBK1TTBK2 | |
| SCHEMBL28798529 | 0.82 | TTBK1 (0.48) | AXLNUDT1MAP2K1TTBK1TTBK2 | |
| SCHEMBL29656385 | 0.82 | TTBK1 (0.48) | AXLNUDT1MAP2K1TTBK1TTBK2 | |
| SCHEMBL2115690 | 0.82 | AXL (0.55) | AXLNUDT1MAP2K1TTBK1TTBK2 | |
| SCHEMBL16940954 | 0.81 | JAK3 (0.50) | AXLNUDT1MAP2K1TTBK1TTBK2 | |
| SCHEMBL24455454 | 0.79 | JAK3 (0.51) | AXLNUDT1MAP2K1TTBK1TTBK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116779-A1 | DIALKYNE COMPOUND AND USE THEREOF | 上海艾力斯医药科技股份有限公司 | 2023-06-29 | — | — | WO | disclosed |
| WO-2023116779-A1 | DIALKYNE COMPOUND AND USE THEREOF | 上海艾力斯医药科技股份有限公司 | 2023-06-29 | — | — | WO | disclosed |