Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | PLAT | P00750 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MAT2A | P31153 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1901245 | 0.78 | ALDH1A1 (0.47) | GAAKDM4EALDH1A1TSHRHSD17B10 | |
| SCHEMBL14192002 | 0.77 | OPRK1 (0.47) | GAAKDM4EALDH1A1POLBLMNA | |
| SCHEMBL19817161 | 0.77 | OPRK1 (0.42) | OPRK1 | |
| SCHEMBL25148734 | 0.75 | PDCD1 (0.44) | GAAKDM4EALDH1A1TSHRNPSR1 | |
| SCHEMBL30364876 | 0.75 | PDCD1 (0.44) | GAAKDM4EALDH1A1TSHRNPSR1 | |
| SCHEMBL28906478 | 0.74 | OPRK1 (0.40) | GAAKDM4EALDH1A1TSHRNPSR1 | |
| SCHEMBL15633425 | 0.73 | KDM4E (0.46) | GAAKDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL16094460 | 0.73 | ATM (0.44) | GAAKDM4EALDH1A1HSD17B10POLB | |
| SCHEMBL24457883 | 0.73 | ALDH1A1 (0.33) | KDM4EALDH1A1TSHRHSD17B10CYP1A2 | |
| SCHEMBL31233771 | 0.72 | SLC6A3 (0.42) | ALDH1A1TSHRNPSR1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023111181-A1 | SMALL MOLECULE MODULATORS OF IL-17 | LEO PHARMA A/S (DK) | 2023-06-22 | — | — | WO | disclosed |
| WO-2023111181-A1 | SMALL MOLECULE MODULATORS OF IL-17 | LEO PHARMA A/S (DK) | 2023-06-22 | — | — | WO | disclosed |