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Sugi Predict / Compounds / SCHEMBL2528200

SCHEMBL2528200

SCHEMBL2528200

O=S(=O)(O)OC[C@H]1O[C@H](O[C@@H]2O[C@H](COS(=O)(=O)O)[C@H](OS(=O)(=O)O)[C@H](OS(=O)(=O)O)[C@H]2OS(=O)(=O)O)[C@H](OS(=O)(=O)O)[C@@H](OS(=O)(=O)O)[C@@H]1O

nearest known ligand 0.62

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ FGF1 P05230 5/20 0.62
▸ FGF2 P09038 2/20 0.62
▸ HPSE Q9Y251 11/20 0.48
▸ SERPINC1 P01008 1/20 0.45
▸ F10 P00742 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2524663 1.00 FGF1 (0.62) FGF1FGF2HPSESERPINC1F10
SCHEMBL4180806 0.93 FGF1 (0.69) FGF1FGF2HPSESERPINC1
SCHEMBL14020073 0.87 FGF1 (0.70) FGF1FGF2HPSESERPINC1
SCHEMBL4906384 0.87 FGF1 (0.70) FGF1FGF2HPSESERPINC1
SCHEMBL4904646 0.87 FGF1 (0.70) FGF1FGF2HPSESERPINC1
SCHEMBL18742104 0.85 FGF1 (0.76) FGF1FGF2HPSESERPINC1
SCHEMBL18742103 0.85 FGF1 (0.76) FGF1FGF2HPSESERPINC1
SCHEMBL7311357 0.85 FGF1 (0.76) FGF1FGF2HPSESERPINC1
SCHEMBL9315067 0.82 FGF1 (0.50) FGF1FGF2HPSESERPINC1F10
SCHEMBL9314016 0.82 FGF1 (0.50) FGF1FGF2HPSESERPINC1F10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2205616-B1 NOVEL SULFATED OLIGOSACCHARIDE DERIVATIVES PROGEN PHARMACEUTICALS LTD (AU) 2016-04-27 — — EP claimed
EP-2205616-B1 NOVEL SULFATED OLIGOSACCHARIDE DERIVATIVES PROGEN PHARMACEUTICALS LTD (AU) 2016-04-27 — — EP disclosed
US-20110245196-A1 NOVEL SULFATED OLIGOSACCHARIDE DERIVATIVES PROGEN PG500 SERIES PTY LTD (AU) 2011-10-06 — — US disclosed
EP-2205616-A1 NOVEL SULFATED OLIGOSACCHARIDE DERIVATIVES Progen Pharmaceuticals Limited (AU) 2010-07-14 — — EP disclosed
WO-2009049370-A1 NOVEL SULFATED OLIGOSACCHARIDE DERIVATIVES PROGEN PHARMACEUTICALS LIMITED (AU) 2009-04-23 — — WO disclosed