SCHEMBL2528210

SCHEMBL2528210

Cc1cc(-c2ccccc2)c(O)c(-c2ccccc2)c1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 2/20 0.54
ESR2 Q92731 1/20 0.52
F2 P00734 1/20 0.49
F10 P00742 1/20 0.49
PLG P00747 1/20 0.49
PLAU P00749 1/20 0.49
PLAT P00750 1/20 0.49
PRSS1 P07477 1/20 0.49
PDE4B Q07343 2/20 0.47
PTPN1 P18031 2/20 0.47
ALOX5 P09917 1/20 0.46
ALDH1A1 P00352 2/20 0.46
HPGD P15428 1/20 0.46
BCL2L1 Q07817 1/20 0.46
HSD17B10 Q99714 1/20 0.46
METAP2 P50579 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC4 P56524 1/20 0.45
HDAC2 Q92769 1/20 0.45
HDAC8 Q9BY41 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11134273 0.98 BACE1 (0.52) BACE1ESR2F2F10PLG
SCHEMBL8986922 0.89 ESR2 (0.52) BACE1ESR2F2F10PLG
SCHEMBL30286418 0.86 RPS6KA3 (0.46) BACE1ESR2F2F10PLG
SCHEMBL5086984 0.86 CRHBP (0.53) BACE1ESR2F2F10PLG
SCHEMBL10014387 0.84 PDCD1 (0.50) BACE1ESR2F2F10PLG
SCHEMBL15498126 0.82 PDCD1 (0.44) BACE1ESR2PTPN1ALDH1A1HPGD
SCHEMBL9651394 0.82 PTPN1 (0.69) PTPN1HPGDHSD17B10HDAC7TSHR
SCHEMBL31027271 0.82 CA2 (0.59) BACE1ESR2F2F10PLG
SCHEMBL27763861 0.82 ESR2 (0.46) BACE1ESR2F2F10PLG
SCHEMBL17500171 0.82 CA2 (0.59) BACE1ESR2F2F10PLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3662996-A2 MOLYBDENUM AND TUNGSTEN COMPLEXES AS OLEFIN METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS Verbio Vereinigte BioEnergie AG (DE) 2020-06-10 EP claimed
EP-2703081-B1 MOLYBDENUM AND TUNGSTEN COMPLEXES AS OLEFIN METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS XIMO AG (CH) 2019-08-07 EP claimed
CN-108250341-A The method of catalyst system and its catalysis in olefine polymerization containing metallocene compound 北京引发科技有限公司 2018-07-06 CN claimed
US-9919299-B2 Metathesis catalysts and reactions using the catalysts XIMO AG (CH) 2018-03-20 US claimed
CN-105555402-A Metathesis catalyst and reaction using the same XIMO AG 2016-05-04 CN claimed
US-20160030936-A1 METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS VERBIO SE (DE) 2016-02-04 US claimed
EP-2969204-A2 MOLYBDENUM AND TUNGSTEN COMPLEXES AS OLEFIN METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS XiMo AG (CH) 2016-01-20 EP claimed
US-20140309466-A1 METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS VERBIO SE (DE) 2014-10-16 US claimed
WO-2014139679-A2 METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS XIMO AG (CH) 2014-09-18 WO claimed
EP-2703081-A1 Molybdenum and tungsten complexes as olefin metathesis catalysts and reactions using the catalysts XiMo AG (CH) 2014-03-05 EP claimed
US-4040911-A ADDING A QUINONE ALKIDE AND A HINDERED PHENOL DURING VACUUM DISTILLATION GULF RESEARCH & DEVELOPMENT COMPANY (US) 1977-08-09 US claimed
US-4032547-A OXIDATION OF HINDERED PHENOLS, FERRICYANIDE AND PERSULFATE OXIDIZERS GULF RESEARCH & DEVELOPMENT COMPANY (US) 1977-06-28 US claimed
US-11779911-B2 Production of fatty olefin derivatives via olefin metathesis PROVIVI, INC. (US) 2023-10-10 US disclosed
EP-4234522-A2 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS Provivi, Inc. (US) 2023-08-30 EP disclosed
EP-3377465-B1 PRODUCTION OF FATTY OLEFIN DERIVATIVES VIA OLEFIN METATHESIS PROVIVI INC (US) 2023-08-02 EP disclosed
CN-110603240-B Synthesis of pheromones and related substances via olefin metathesis 普罗维维公司 2022-11-15 CN disclosed
US-5176976-A Stilbenequinones as stable charge transfer compounds CANON KABUSHIKI KAISHA (JP) 1993-01-05 US disclosed
EP-0451761-A1 Organic electronic material and electrophotographic photosensitive member containing it CANON KABUSHIKI KAISHA (JP) 1991-10-16 EP disclosed
US-4040911-A ADDING A QUINONE ALKIDE AND A HINDERED PHENOL DURING VACUUM DISTILLATION GULF RESEARCH & DEVELOPMENT COMPANY (US) 1977-08-09 US disclosed
US-4032547-A OXIDATION OF HINDERED PHENOLS, FERRICYANIDE AND PERSULFATE OXIDIZERS GULF RESEARCH & DEVELOPMENT COMPANY (US) 1977-06-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140309466-A1 METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS MSMO1, PYM1, SQLE BACE1 1981/4885ESR2 709/4885F2 156/4885
US-20160030936-A1 METATHESIS CATALYSTS AND REACTIONS USING THE CATALYSTS MSMO1, SQLE, PYM1 BACE1 1787/4885ESR2 778/4885F2 159/4885
US-11779911-B2 Production of fatty olefin derivatives via olefin metathesis SREBF1, F2, SREBF2 BACE1 289/4885ESR2 214/4885F2 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.