SCHEMBL8986922

SCHEMBL8986922

Cc1cc(C)c(O)c(-c2ccccc2)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 1/20 0.52
BACE1 P56817 2/20 0.48
PSMB5 P28074 1/20 0.46
ALDH1A1 P00352 5/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
LMNA P02545 3/20 0.43
GAA P10253 2/20 0.43
MAPT P10636 2/20 0.43
KDM4E B2RXH2 1/20 0.43
PDE4B Q07343 1/20 0.43
PTPN1 P18031 1/20 0.43
F2 P00734 1/20 0.43
F10 P00742 1/20 0.43
PLG P00747 1/20 0.43
PLAU P00749 1/20 0.43
PLAT P00750 1/20 0.43
PRSS1 P07477 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.42
MCOLN3 Q8TDD5 1/20 0.42
ALOX5 P09917 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2528210 0.89 BACE1 (0.54) ESR2BACE1PSMB5ALDH1A1PDE4B
SCHEMBL11134273 0.87 BACE1 (0.52) ESR2BACE1PSMB5ALDH1A1PDE4B
SCHEMBL172874 0.85 CA1 (0.54) ESR2BACE1ALDH1A1LMNAPDE4B
SCHEMBL31028131 0.85 CA1 (0.54) ESR2BACE1ALDH1A1LMNAPDE4B
SCHEMBL2861284 0.83 ESR2 (0.62) ESR2BACE1ALDH1A1LMNAMAPT
SCHEMBL22500696 0.83 GAA (0.44) ESR2ALDH1A1LMNAGAAMAPT
SCHEMBL17500081 0.81 HDAC4 (0.53) ESR2ALDH1A1L3MBTL1SMN1; SMN2ALOX5
SCHEMBL27734232 0.81 ESR2 (0.53) ESR2BACE1ALDH1A1LMNAPDE4B
SCHEMBL13997558 0.80 AKR1C3 (0.59) ESR2BACE1ALDH1A1LMNAPDE4B
SCHEMBL15516521 0.80 FYN (0.50) ALDH1A1LMNAGAAMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190181409-A1 HIGH TEMPERATURE MELT INTEGRITY BATTERY SEPARATORS VIA SPINNING SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-06-13 US disclosed
US-10243187-B2 Process of making battery separators via spinning SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-03-26 US disclosed
CN-105142605-B 1, 2-alkane polyol-containing composition 大阪有机化学工业株式会社 2018-06-08 CN disclosed
US-9795549-B2 1,2-alkane polyol-containing composition OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) 2017-10-24 US disclosed
US-9577235-B2 High temperature melt integrity battery separators via spinning SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-02-21 US disclosed
US-20160348281-A1 High Temperature Melt Integrity Battery Separators Via Spinning SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2016-12-01 US disclosed
CN-105431576-A High temperature melt integrity battery separators via spinning SABIC INNOVATIVE PLASTICS IP 2016-03-23 CN disclosed
US-20160045414-A1 1,2-ALKANE POLYOL-CONTAINING COMPOSITION OSAKA ORGANIC CHEMICAL INDUSTRY LTD. (JP) 2016-02-18 US disclosed
EP-2985017-A1 1,2-ALKANE POLYOL-CONTAINING COMPOSITION Osaka Organic Chemical Ind., Ltd. (JP) 2016-02-17 EP disclosed
CN-105142605-A 1, 2-alkane polyol-containing composition OSAKA ORGANIC CHEM IND 2015-12-09 CN disclosed
EP-2935665-A2 HIGH TEMPERATURE MELT INTEGRITY BATTERY SEPARATORS VIA SPINNING SABIC Global Technologies B.V. (NL) 2015-10-28 EP disclosed
WO-2014100213-A2 HIGH TEMPERATURE MELT INTEGRITY BATTERY SEPARATORS VIA SPINNING SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-06-26 WO disclosed
US-20140167329-A1 HIGH TEMPERATURE MELT INTEGRITY BATTERY SEPARATORS VIA SPINNING SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-06-19 US disclosed
EP-0451761-B1 Organic electronic material and electrophotographic photosensitive member containing it CANON KK (JP) 1996-07-03 EP disclosed
US-5176976-A Stilbenequinones as stable charge transfer compounds CANON KABUSHIKI KAISHA (JP) 1993-01-05 US disclosed
EP-0451761-A1 Organic electronic material and electrophotographic photosensitive member containing it CANON KABUSHIKI KAISHA (JP) 1991-10-16 EP disclosed
EP-0095078-B1 STABILIZED OLEFIN POLYMER COMPOSITIONS AND THEIR USE FOR PREPARING SHAPED ARTICLES BORG-WARNER CHEMICALS INC. (US) 1986-07-02 EP disclosed
US-4562211-A ANTIDEPRESSANTS MITSUBISHI CHEMICAL INDUSTRIES, LTD. (JP) 1985-12-31 US disclosed