SCHEMBL25282500

SCHEMBL25282500

CCOC(=O)COC(=O)c1cc([N+](=O)[O-])c(F)cc1Cl

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.46
GUSB P08236 1/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2C19 P33261 1/20 0.46
MAPT P10636 5/20 0.45
LMNA P02545 3/20 0.45
SMN1; SMN2 Q16637 3/20 0.45
NPSR1 Q6W5P4 3/20 0.45
HPGD P15428 2/20 0.45
POLB P06746 2/20 0.45
ALDH1A1 P00352 2/20 0.45
MITF O75030 2/20 0.45
GALR2 O43603 1/20 0.45
HSP90AA1 P07900 1/20 0.45
XBP1 P17861 1/20 0.45
CCR6 P51684 1/20 0.45
TDP1 Q9NUW8 1/20 0.43
HTT P42858 2/20 0.41
NPC1 O15118 1/20 0.40
MAPK1 P28482 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3064007 0.91 LMNA (0.53) GAAGUSBCYP1A2CYP2C19MAPT
SCHEMBL30483100 0.88 GUSB (0.49) GAAGUSBCYP1A2CYP2C19MAPT
SCHEMBL3598981 0.86 LMNA (0.50) GUSBCYP1A2CYP2C19MAPTLMNA
SCHEMBL1301604 0.84 LMNA (0.43) GAAGUSBCYP1A2CYP2C19MAPT
SCHEMBL25293637 0.84 LMNA (0.42) GAAGUSBCYP1A2CYP2C19MAPT
SCHEMBL25293636 0.84 LMNA (0.42) GAAGUSBCYP1A2CYP2C19MAPT
SCHEMBL18342871 0.81 MAPT (0.52) GAACYP1A2CYP2C19MAPTLMNA
SCHEMBL16063534 0.81 ALDH1A1 (0.42) GUSBCYP1A2CYP2C19MAPTLMNA
SCHEMBL25285977 0.81 SMN1; SMN2 (0.44) GAAGUSBCYP1A2CYP2C19MAPT
SCHEMBL24151272 0.81 SMN1; SMN2 (0.44) GAAGUSBCYP1A2CYP2C19MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250127170-A1 TRIAZINE HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-04-24 US disclosed
EP-4452953-A1 TRIAZINE HERBICIDAL COMPOUNDS Syngenta Crop Protection AG (CH) 2024-10-30 EP disclosed
CN-118339147-A Triazine herbicidal compounds 先正达农作物保护股份公司 2024-07-12 CN disclosed
WO-2023117670-A1 TRIAZINE HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2023-06-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250127170-A1 TRIAZINE HERBICIDAL COMPOUNDS DDT, DPP7, PTPRZ1 GAA 649/4885GUSB 228/4885CYP1A2 236/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.