SCHEMBL3064007

SCHEMBL3064007

CCOC(=O)c1cc([N+](=O)[O-])c(F)cc1Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.53
ALDH1A1 P00352 3/20 0.53
SMN1; SMN2 Q16637 3/20 0.53
POLB P06746 2/20 0.53
HPGD P15428 2/20 0.53
GALR2 O43603 1/20 0.53
MITF O75030 1/20 0.53
HSP90AA1 P07900 1/20 0.53
XBP1 P17861 1/20 0.53
CCR6 P51684 1/20 0.53
NPSR1 Q6W5P4 1/20 0.53
GUSB P08236 1/20 0.50
MAPT P10636 2/20 0.45
CYP4F2 P78329 1/20 0.45
CYP4A11 Q02928 1/20 0.45
BAZ2B Q9UIF8 1/20 0.45
BAZ2A Q9UIF9 1/20 0.45
NPC1 O15118 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3598981 0.94 LMNA (0.50) LMNAALDH1A1SMN1; SMN2POLBHPGD
SCHEMBL25282500 0.91 GAA (0.46) LMNAALDH1A1SMN1; SMN2POLBHPGD
SCHEMBL30483100 0.89 GUSB (0.49) LMNAALDH1A1SMN1; SMN2POLBHPGD
SCHEMBL670959 0.87 ALDH1A1 (0.57) LMNAALDH1A1SMN1; SMN2POLBHPGD
SCHEMBL16063534 0.86 ALDH1A1 (0.42) LMNAALDH1A1SMN1; SMN2POLBHPGD
SCHEMBL24151272 0.86 SMN1; SMN2 (0.44) LMNAALDH1A1SMN1; SMN2POLBHPGD
SCHEMBL25285977 0.86 SMN1; SMN2 (0.44) LMNAALDH1A1SMN1; SMN2POLBHPGD
SCHEMBL10003178 0.86 ALDH1A1 (0.56) LMNAALDH1A1SMN1; SMN2POLBHPGD
SCHEMBL9587174 0.85 THRB (0.44) LMNAALDH1A1SMN1; SMN2POLBHPGD
SCHEMBL10003869 0.84 ALDH1A1 (0.54) LMNAALDH1A1SMN1; SMN2POLBHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260085051-A1 PREPARATION OF 2-CHLORO-4-FLUORO-5-NITROBENZOIC ACID ADAMA AGAN LTD. (IL) 2026-03-26 US disclosed
EP-4313954-B1 PREPARATION OF 2-CHLORO-4-FLUORO-5-NITROBENZOIC ACID ADAMA AGAN LTD (IL) 2025-10-15 EP disclosed
US-20250127170-A1 TRIAZINE HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-04-24 US disclosed
US-20250115560-A1 A NEW PROCESS OF SAFLUFENACIL PRODUCTION USING NOVEL INTERMEDIATES ADAMA AGAN LTD (IL) 2025-04-10 US disclosed
CN-119790033-A Preparation of 2-chloro-4-fluoro-5-nitrobenzoic acid 安道麦阿甘有限公司 2025-04-08 CN disclosed
US-20250109112-A1 HERBICIDAL COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-04-03 US disclosed
EP-4469443-A1 HERBICIDAL COMPOUNDS Syngenta Crop Protection AG (CH) 2024-12-04 EP disclosed
EP-4452953-A1 TRIAZINE HERBICIDAL COMPOUNDS Syngenta Crop Protection AG (CH) 2024-10-30 EP disclosed
US-12091425-B2 Compounds that inhibit MCL-1 protein AMGEN INC. (US) 2024-09-17 US disclosed
CN-118591531-A Herbicidal compounds 先正达农作物保护股份公司 2024-09-03 CN disclosed
US-20060223810-A1 Bicyclic pyrazole compounds as antibacterial agents JANSSEN PHARMACEUTICA N.V. (BE) 2006-10-05 US disclosed
WO-2006105289-A1 BICYCLIC PYRAZOLE COMPOUNDS AS ANTIBACTERIAL AGENTS JANSSEN PHARMACEUTICA N.V. (BE) 2006-10-05 WO disclosed
US-6869913-B1 Pyridazin-3-one derivatives, their use and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2005-03-22 US disclosed
US-6703503-B2 HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-03-09 US disclosed
US-20040005986-A1 Pyridazin-3-one derivatives, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2004-01-08 US disclosed
US-6482773-B1 Pyridazin-3-one derivatives, their use, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-11-19 US disclosed
US-6348628-B1 HYDRAZONE HERBICIDE INTERMEDIATES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-02-19 US disclosed
US-6090753-A 2-(SUBSTITUTED PHENYL), 5-HALOALKYL-PYRIDAZIN-3-ONE DERIVATIVES AS HERBICIDES; CONTROLLING WEEDS, METHOD OF MAKING BY REACTING A HYDRAZONE DERIVATIVE WITH A SPECIFIED PHOSPHORUS COMPOUND SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2000-07-18 US disclosed
EP-0850227-A1 PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1998-07-01 EP disclosed
WO-1997007104-A1 PYRIDAZIN-3-ONE DERIVATIVES, THEIR USE, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-02-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060223810-A1 Bicyclic pyrazole compounds as antibacterial agents NOD2, BAK1, CASP3 LMNA 2909/4885ALDH1A1 3885/4885SMN1; SMN2 4696/4885
US-20250109112-A1 HERBICIDAL COMPOUNDS DDT, ACHE, DPP7 LMNA 4384/4885ALDH1A1 62/4885SMN1; SMN2 2348/4885
US-20040005986-A1 Pyridazin-3-one derivatives, their use, and intermediates for their production Q6ZSR9, HDHD5, CBR3 LMNA 3128/4885ALDH1A1 330/4885SMN1; SMN2 4801/4885
US-20250115560-A1 A NEW PROCESS OF SAFLUFENACIL PRODUCTION USING NOVEL INTERMEDIATES DPYD, PDK1, CYP2S1 LMNA 2283/4885ALDH1A1 111/4885SMN1; SMN2 2907/4885
US-20260085051-A1 PREPARATION OF 2-CHLORO-4-FLUORO-5-NITROBENZOIC ACID FOSB, DDT, NPM1 LMNA 3750/4885ALDH1A1 1129/4885SMN1; SMN2 3239/4885
US-20250127170-A1 TRIAZINE HERBICIDAL COMPOUNDS DDT, DPP7, PTPRZ1 LMNA 4716/4885ALDH1A1 219/4885SMN1; SMN2 3579/4885
US-12091425-B2 Compounds that inhibit MCL-1 protein MCL1, BCL9, BCL2L1 LMNA 1191/4885ALDH1A1 1891/4885SMN1; SMN2 1807/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.