SCHEMBL25282932

SCHEMBL25282932

CCN(CCOC(=O)c1ccc(N)cc1)CCc1cc(N)ccc1C(=O)O

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 5/20 0.65
HRH3 Q9Y5N1 4/20 0.65
MAOA P21397 4/20 0.65
TSHR P16473 4/20 0.65
HTR3A P46098 2/20 0.65
BLM P54132 1/20 0.64
NPSR1 Q6W5P4 1/20 0.64
KCNH2 Q12809 4/20 0.55
CHRM2 P08172 2/20 0.55
CHRM3 P20309 1/20 0.55
HTR2C P28335 1/20 0.55
CHRNA4 P43681 1/20 0.55
SCN1A P35498 6/20 0.52
SCN2A Q99250 6/20 0.52
SCN3A Q9NY46 6/20 0.52
CYP1A2 P05177 6/20 0.52
PHLPP2 Q6ZVD8 1/20 0.51
LMNA P02545 5/20 0.49
CYP3A4 P08684 4/20 0.49
SLC6A3 Q01959 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Procaine SCHEMBL174070 0.98 CYP2D6 (0.69) CYP2D6HRH3MAOATSHRHTR3A
SCHEMBL31070925 0.83 MAOA (0.49) CYP2D6HRH3MAOATSHRHTR3A
SCHEMBL1568843 0.83 MAOA (0.49) CYP2D6HRH3MAOATSHRHTR3A
SCHEMBL25239695 0.83 CYP2D6 (0.94) CYP2D6HRH3MAOATSHRHTR3A
Hydrochloric Acid SCHEMBL7238288 0.82 ACHE (0.50) CYP2D6HRH3MAOATSHRHTR3A
Procaine SCHEMBL1022025 0.80 CYP2D6 (0.94) CYP2D6HRH3MAOATSHRHTR3A
Amoxecaine SCHEMBL1230983 0.80 CYP2D6 (0.94) CYP2D6HRH3MAOATSHRHTR3A
Procaine SCHEMBL1021261 0.80 CYP2D6 (0.94) CYP2D6HRH3MAOATSHRHTR3A
Procaine SCHEMBL3524 0.80 CYP2D6 (1.00) CYP2D6HRH3MAOATSHRHTR3A
SCHEMBL6440224 0.80 MAPT (0.58) CYP2D6HRH3MAOATSHRHTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114262337-A Procaine penicillin, preparation method thereof, impurities and impurity control method 华北制药集团先泰药业有限公司 2022-04-01 CN claimed
WO-2023109157-A1 PROCAINE PENICILLIN AND PREPARATION METHOD THEREFOR, AND IMPURITY AND IMPURITY CONTROL METHOD 华北制药集团先泰药业有限公司 2023-06-22 WO disclosed
WO-2023109157-A1 PROCAINE PENICILLIN AND PREPARATION METHOD THEREFOR, AND IMPURITY AND IMPURITY CONTROL METHOD 华北制药集团先泰药业有限公司 2023-06-22 WO disclosed
CN-114262337-A Procaine penicillin, preparation method thereof, impurities and impurity control method 华北制药集团先泰药业有限公司 2022-04-01 CN disclosed
CN-114262337-A Procaine penicillin, preparation method thereof, impurities and impurity control method 华北制药集团先泰药业有限公司 2022-04-01 CN disclosed