Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.49 |
| ▸ | HTR3A | P46098 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.49 |
| ▸ | HTR2C | P28335 | 1/20 | 0.49 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | PRKCI | P41743 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | SCN1A | P35498 | 1/20 | 0.46 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.46 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1568843 | 1.00 | MAOA (0.49) | MAOAHTR3AHRH3CHRM2CHRM3 | |
| Hydrochloric Acid SCHEMBL7238288 | 0.98 | ACHE (0.50) | MAOAHTR3AHRH3CHRM2CHRM3 | |
| Procaine SCHEMBL174070 | 0.86 | CYP2D6 (0.69) | MAOAHTR3AHRH3CHRM2CHRM3 | |
| SCHEMBL9128007 | 0.84 | MAPT (0.47) | MAOAHTR3AHRH3CHRM2CHRM3 | |
| SCHEMBL16039694 | 0.83 | CSNK2A1 (0.42) | SCN1ASCN2ASCN3AALDH1A1MAPT | |
| SCHEMBL25282932 | 0.83 | CYP2D6 (0.65) | MAOAHTR3AHRH3CHRM2CHRM3 | |
| SCHEMBL1931833 | 0.82 | MAPT (0.52) | PRKCIACHEALDH1A1MAPTKDM4E | |
| SCHEMBL28062236 | 0.82 | ALDH1A1 (0.59) | CYP1A2ALDH1A1MAPTKDM4ECYP3A4 | |
| SCHEMBL3325487 | 0.80 | CA2 (0.45) | ALDH1A1KDM4ECYP2C19MAPK1TDP1 | |
| SCHEMBL182142 | 0.80 | ALDH1A1 (0.57) | PRKCIACHEALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118354759-A | Compositions comprising 2' -deoxycytidine analogs and their use for treating sickle cell disease, thalassemia and cancer | 阿基拉比奥有限公司 | 2024-07-16 | — | — | CN | disclosed |