Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31022641 | 0.76 | KDM4E (0.34) | KDM4E | |
| SCHEMBL31022679 | 0.73 | ERN1 (0.54) | EGLN1ALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL25238932 | 0.64 | — | — | |
| SCHEMBL12814747 | 0.63 | KDM4E (0.45) | MEN1KMT2AALDH1A1RAB9AKDM4E | |
| SCHEMBL31022701 | 0.62 | CA12 (0.57) | EGLN1KMT2AALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL25235346 | 0.62 | CA12 (0.57) | EGLN1KMT2AALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL16040593 | 0.62 | ALDH1A1 (0.60) | EGLN1MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL31057838 | 0.62 | ALDH1A1 (0.60) | EGLN1MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL8564487 | 0.61 | CYP1A2 (0.50) | KMT2AALDH1A1RAB9AKDM4ENPC1 | |
| SCHEMBL7893039 | 0.60 | CYP3A4 (0.55) | MEN1KMT2AALDH1A1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023120696-A1 | 1H-PYRAZOLE-3-AMINE DERIVATIVE HAVING BICYCLIC BACKBONE | 住友ファーマ株式会社 | 2023-06-29 | — | — | WO | disclosed |