Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.32 |
| ▸ | KCNC1 | P48547 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25238932 | 0.84 | — | — | |
| SCHEMBL12814747 | 0.83 | KDM4E (0.45) | KDM4EPDGFRBPDGFRAKCNC1 | |
| SCHEMBL25283142 | 0.76 | EGLN1 (0.35) | KDM4E | |
| SCHEMBL14805709 | 0.75 | KDM4E (0.32) | KDM4E | |
| SCHEMBL12896074 | 0.75 | ALDH1A1 (0.35) | KDM4E | |
| SCHEMBL8564487 | 0.70 | CYP1A2 (0.50) | KDM4EPDGFRBPDGFRA | |
| SCHEMBL17541419 | 0.70 | MRGPRX4 (0.47) | — | |
| SCHEMBL827713 | 0.70 | CYP1A2 (0.44) | KDM4EKCNC1 | |
| SCHEMBL31168473 | 0.70 | CYP1A2 (0.44) | KDM4EKCNC1 | |
| SCHEMBL10855251 | 0.69 | NOS3 (0.36) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250129049-A1 | 1H-PYRAZOLE-3-AMINE DERIVATIVE HAVING BICYCLIC BACKBONE | Sumitomo Pharma Co., Ltd. (JP) | 2025-04-24 | — | — | US | disclosed |
| EP-4455134-A1 | 1H-PYRAZOLE-3-AMINE DERIVATIVE HAVING BICYCLIC BACKBONE | Sumitomo Pharma Co., Ltd. (JP) | 2024-10-30 | — | — | EP | disclosed |
| CN-118434726-A | 1H-pyrazol-3-amine derivatives having a bicyclic skeleton | 住友制药株式会社 | 2024-08-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250129049-A1 | 1H-PYRAZOLE-3-AMINE DERIVATIVE HAVING BICYCLIC BACKBONE | CHEK1, BUB1B, CHEK2 | KDM4E 902/4885F2RL3 4473/4885PDGFRB 2048/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.