Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 2/20 | 0.53 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.46 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.34 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL7490955 | 0.81 | CYP2A6 (0.54) | CYP2A6PDPK1LOXL2CHEK2CYP11B1 | |
| SCHEMBL14908855 | 0.78 | CYP2A6 (0.53) | CYP2A6PDPK1LOXL2SMPD3ADRB2 | |
| SCHEMBL3386179 | 0.78 | CYP2A6 (0.53) | CYP2A6PDPK1LOXL2SMPD3ADRB2 | |
| SCHEMBL2715410 | 0.78 | CYP2A6 (0.53) | CYP2A6PDPK1LOXL2SMPD3ADRB2 | |
| SCHEMBL20153302 | 0.78 | CYP2A6 (0.54) | CYP2A6PDPK1LOXL2SMPD3ADRB2 | |
| SCHEMBL20422071 | 0.77 | CYP2A6 (0.49) | CYP2A6PDPK1LOXL2SMPD3ADRB2 | |
| SCHEMBL7079127 | 0.75 | PDPK1 (0.67) | CYP2A6PDPK1LOXL2ADRB2CHEK2 | |
| SCHEMBL173979 | 0.74 | PDPK1 (0.60) | CYP2A6PDPK1LOXL2ADRB2KMT2A | |
| SCHEMBL3327398 | 0.74 | CYP2A6 (0.62) | CYP2A6PDPK1LOXL2SMPD3ADRB2 | |
| SCHEMBL16159900 | 0.74 | CYP2A6 (0.53) | CYP2A6PDPK1LOXL2SMPD3ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2585451-B1 | HETEROCYCLIC COMPOUNDS AS AGENTS FOR PEST CONTROL | BAYER IP GMBH (DE) | 2017-03-01 | — | — | EP | disclosed |
| EP-2585451-B1 | HETEROCYCLIC COMPOUNDS AS AGENTS FOR PEST CONTROL | BAYER IP GMBH (DE) | 2017-03-01 | — | — | EP | disclosed |
| US-9044015-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2015-06-02 | — | — | US | disclosed |
| US-9044015-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2015-06-02 | — | — | US | disclosed |
| US-9044015-B2 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2015-06-02 | — | — | US | disclosed |
| US-20140148471-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2014-05-29 | — | — | US | disclosed |
| US-20140148471-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2014-05-29 | — | — | US | disclosed |
| US-20140148471-A1 | Heterocyclic Compounds as Pesticides | BAYER CROPSCIENCE AG (DE) | 2014-05-29 | — | — | US | disclosed |
| EP-2585451-A2 | HETEROCYCLIC COMPOUNDS AS AGENTS FOR PEST CONTROL | Bayer Intellectual Property GmbH (DE) | 2013-05-01 | — | — | EP | disclosed |
| US-20120165345-A1 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-06-28 | — | — | US | disclosed |
| US-20120165345-A1 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-06-28 | — | — | US | disclosed |
| US-20120165345-A1 | Heterocyclic compounds as pesticides | BAYER CROPSCIENCE AG (DE) | 2012-06-28 | — | — | US | disclosed |
| WO-2012000896-A2 | HETEROCYCLIC COMPOUNDS AS AGENTS FOR PEST CONTROL | BAYER CROPSCIENCE AG (DE) | 2012-01-05 | — | — | WO | disclosed |
| WO-2012000896-A2 | HETEROCYCLIC COMPOUNDS AS AGENTS FOR PEST CONTROL | BAYER CROPSCIENCE AG (DE) | 2012-01-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148471-A1 | Heterocyclic Compounds as Pesticides | DDT, ACHE, PTMS | CYP2A6 777/4885PDPK1 364/4885LOXL2 928/4885 |
| US-20120165345-A1 | Heterocyclic compounds as pesticides | DDT, ACHE, PTMS | CYP2A6 777/4885PDPK1 364/4885LOXL2 928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.