SCHEMBL2528376

SCHEMBL2528376

C=CC([CH]CCCC)OCC

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
ALDH1A1 P00352 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10071573 0.77
SCHEMBL16287785 0.69
SCHEMBL10071571 0.69 TSHR (0.40) TSHRALDH1A1
SCHEMBL10071572 0.67 DNM1 (0.43) TSHRALDH1A1
SCHEMBL196197 0.67
SCHEMBL5847747 0.67
SCHEMBL3045930 0.67
SCHEMBL16288370 0.67 TSHR (0.46) TSHRALDH1A1
SCHEMBL195947 0.67 TSHR (0.41) TSHRALDH1A1
SCHEMBL10071568 0.65 DNM1 (0.47) TSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090032461-A1 METHOD FOR SEPARATING POLYMER SYSTEMS AND PORE-FREE POLYMER FILMS USED IN SAID METHOD PHILIPPS-UNIVERSITAT MARBURG (DE) 2009-02-05 US claimed
US-20050239808-A1 Active substances for the treatment, diagnosis and prophylaxis of diseases in which abnormal protein structures occur TRANSMIT GESELLSCHAFT FUR TECHNOLOGIETRANSFER MBH (DE) 2005-10-27 US claimed
US-8431064-B2 Method of using nanoscaled polymer fibers as carriers for agricultural substances PHILLIPS-UNIVERSITAT MARBURG (DE) 2013-04-30 US disclosed
US-8017061-B2 Invention concerning agricultural active substances PHILIPPS-UNIVERSITAT MARBURG (DE) 2011-09-13 US disclosed
US-20090032461-A1 METHOD FOR SEPARATING POLYMER SYSTEMS AND PORE-FREE POLYMER FILMS USED IN SAID METHOD PHILIPPS-UNIVERSITAT MARBURG (DE) 2009-02-05 US disclosed
US-20080213590-A1 Invention Concerning Agricultural Active Substances JUSTUS-LIEBIG-UNIVERSITAT GIESSEN (DE) 2008-09-04 US disclosed
US-20050239808-A1 Active substances for the treatment, diagnosis and prophylaxis of diseases in which abnormal protein structures occur TRANSMIT GESELLSCHAFT FUR TECHNOLOGIETRANSFER MBH (DE) 2005-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050239808-A1 Active substances for the treatment, diagnosis and prophylaxis of diseases in which abnormal protein structures occur PRNP, APP, MAPT TSHR 4200/4885ALDH1A1 1606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.