Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.57 |
| ▸ | FAAH | O00519 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.55 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.55 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.55 |
| ▸ | PRKCA | P17252 | 1/20 | 0.55 |
| ▸ | TERT | O14746 | 3/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.53 |
| ▸ | PPARG | P37231 | 3/20 | 0.53 |
| ▸ | PPARD | Q03181 | 3/20 | 0.53 |
| ▸ | PPARA | Q07869 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | FABP4 | P15090 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29119323 | 1.00 | DGKA (0.57) | DGKAFAAHTSHRPRKCEPRKCQ | |
| SCHEMBL31024466 | 1.00 | DGKA (0.57) | DGKAFAAHTSHRPRKCEPRKCQ | |
| SCHEMBL20262175 | 1.00 | DGKA (0.57) | DGKAFAAHTSHRPRKCEPRKCQ | |
| SCHEMBL21461637 | 1.00 | DGKA (0.57) | DGKAFAAHTSHRPRKCEPRKCQ | |
| SCHEMBL25239451 | 1.00 | DGKA (0.57) | DGKAFAAHTSHRPRKCEPRKCQ | |
| SCHEMBL31376706 | 1.00 | DGKA (0.57) | DGKAFAAHTSHRPRKCEPRKCQ | |
| SCHEMBL24588792 | 1.00 | DGKA (0.57) | DGKAFAAHTSHRPRKCEPRKCQ | |
| SCHEMBL24588632 | 1.00 | DGKA (0.57) | DGKAFAAHTSHRPRKCEPRKCQ | |
| SCHEMBL20500791 | 1.00 | DGKA (0.57) | DGKAFAAHTSHRPRKCEPRKCQ | |
| SCHEMBL20262173 | 1.00 | DGKA (0.57) | DGKAFAAHTSHRPRKCEPRKCQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4452930-A1 | IONIZABLE AMINE AND ESTER LIPIDS AND LIPID NANOPARTICLES | Beam Therapeutics Inc. (US) | 2024-10-30 | — | — | EP | disclosed |
| US-20240335543-A1 | IONIZABLE AMINE AND ESTER LIPIDS AND LIPID NANOPARTICLES | BEAM THERAPEUTICS INC. | 2024-10-10 | — | — | US | disclosed |
| WO-2023121970-A1 | IONIZABLE AMINE AND ESTER LIPIDS AND LIPID NANOPARTICLES | BEAM THERAPEUTICS INC. (US) | 2023-06-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240335543-A1 | IONIZABLE AMINE AND ESTER LIPIDS AND LIPID NANOPARTICLES | PHOSPHO1, SGMS1, SGMS2 | DGKA 178/4885FAAH 276/4885TSHR 1680/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.