SCHEMBL20262175

SCHEMBL20262175

CCCCCCC=CCOC(=O)CCCCCBr

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DGKA P23743 1/20 0.57
FAAH O00519 3/20 0.57
TSHR P16473 1/20 0.57
PRKCE Q02156 1/20 0.55
PRKCQ Q04759 1/20 0.55
PRKCD Q05655 1/20 0.55
PRKCA P17252 1/20 0.55
TERT O14746 3/20 0.53
PTPN1 P18031 3/20 0.53
PPARG P37231 3/20 0.53
PPARD Q03181 3/20 0.53
PPARA Q07869 3/20 0.53
CYP1A2 P05177 2/20 0.53
MAPT P10636 2/20 0.53
CYP2C19 P33261 2/20 0.53
BLM P54132 2/20 0.53
HSD17B10 Q99714 2/20 0.53
FABP4 P15090 2/20 0.53
KMT2A Q03164 2/20 0.53
GMNN O75496 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29119323 1.00 DGKA (0.57) DGKAFAAHTSHRPRKCEPRKCQ
SCHEMBL31024466 1.00 DGKA (0.57) DGKAFAAHTSHRPRKCEPRKCQ
SCHEMBL21461637 1.00 DGKA (0.57) DGKAFAAHTSHRPRKCEPRKCQ
SCHEMBL25239451 1.00 DGKA (0.57) DGKAFAAHTSHRPRKCEPRKCQ
SCHEMBL31376706 1.00 DGKA (0.57) DGKAFAAHTSHRPRKCEPRKCQ
SCHEMBL24588792 1.00 DGKA (0.57) DGKAFAAHTSHRPRKCEPRKCQ
SCHEMBL25285196 1.00 DGKA (0.57) DGKAFAAHTSHRPRKCEPRKCQ
SCHEMBL24588632 1.00 DGKA (0.57) DGKAFAAHTSHRPRKCEPRKCQ
SCHEMBL20500791 1.00 DGKA (0.57) DGKAFAAHTSHRPRKCEPRKCQ
SCHEMBL20262173 1.00 DGKA (0.57) DGKAFAAHTSHRPRKCEPRKCQ

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12637422-B2 Ionizable cationic lipid for RNA delivery ARCTURUS THERAPEUTICS, INC. (US) 2026-05-26 US disclosed
US-20260131020-A1 IONIZABLE CATIONIC LIPID FOR RNA DELIVERY ARCTURUS THERAPEUTICS INC (US) 2026-05-14 US disclosed
US-12527881-B2 Ionizable cationic lipid for RNA delivery ARCTURUS THERAPEUTICS, INC. (US) 2026-01-20 US disclosed
EP-4678629-A1 IONIZABLE LIPID MOLECULE, PREPARATION METHOD THEREFOR AND USE THEREOF Maxirna (Shanghai) Pharmaceutical Co., Ltd. (CN) 2026-01-14 EP disclosed
EP-4527831-A2 IONIZABLE CATIONIC LIPID FOR RNA DELIVERY Arcturus Therapeutics, Inc. (US) 2025-03-26 EP disclosed
WO-2024183821-A1 IONIZABLE LIPID MOLECULE, PREPARATION METHOD THEREFOR AND USE THEREOF 上海吉量医药工程有限公司 2024-09-12 WO disclosed
EP-4310075-A2 IONIZABLE CATIONIC LIPID FOR RNA DELIVERY Arcturus Therapeutics, Inc. (US) 2024-01-24 EP disclosed
EP-3558943-B1 IONIZABLE CATIONIC LIPID FOR RNA DELIVERY ARCTURUS THERAPEUTICS INC (US) 2023-10-18 EP disclosed
EP-3558942-B1 IONIZABLE CATIONIC LIPID FOR RNA DELIVERY ARCTURUS THERAPEUTICS INC (US) 2023-09-06 EP disclosed
CN-114917203-A Ionizable cationic lipids for RNA delivery 阿克丘勒斯治疗公司 2022-08-19 CN disclosed
CN-110325511-B Ionizable cationic lipids for RNA delivery 阿克丘勒斯治疗公司 2022-04-19 CN disclosed
CN-110337429-B Ionizable cationic lipids for RNA delivery 阿克丘勒斯治疗公司 2021-12-21 CN disclosed
US-20210323914-A1 IONIZABLE CATIONIC LIPID FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. 2021-10-21 US disclosed
US-20210252163-A1 IONIZABLE CATIONIC LIPID FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. 2021-08-19 US disclosed
US-10980895-B2 Ionizable cationic lipid for RNA delivery ARCTURUS THERAPEUTICS, INC. (US) 2021-04-20 US disclosed
US-10961188-B2 Ionizable cationic lipid for RNA delivery ARCTURUS THERAPEUTICS, INC. (US) 2021-03-30 US disclosed
US-20200109113-A1 IONIZABLE CATIONIC LIPID FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. 2020-04-09 US disclosed
US-10383952-B2 Ionizable cationic lipid for RNA delivery ARCTURUS THERAPEUTICS, INC. (US) 2019-08-20 US disclosed
US-20180170866-A1 IONIZABLE CATIONIC LIPID FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. 2018-06-21 US disclosed
US-20180169268-A1 IONIZABLE CATIONIC LIPID FOR RNA DELIVERY ARCTURUS THERAPEUTICS, INC. 2018-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200109113-A1 IONIZABLE CATIONIC LIPID FOR RNA DELIVERY RNASEH1, RNASE1, HNRNPA1 DGKA 3178/4885FAAH 1713/4885TSHR 941/4885
US-20210252163-A1 IONIZABLE CATIONIC LIPID FOR RNA DELIVERY RNASEH1, RNASE1, HNRNPA1 DGKA 3301/4885FAAH 1861/4885TSHR 817/4885
US-10961188-B2 Ionizable cationic lipid for RNA delivery RNASEH1, RNASE1, HNRNPA1 DGKA 3178/4885FAAH 1713/4885TSHR 941/4885
US-10980895-B2 Ionizable cationic lipid for RNA delivery RNASEH1, RNASE1, HNRNPA1 DGKA 3301/4885FAAH 1861/4885TSHR 817/4885
US-10383952-B2 Ionizable cationic lipid for RNA delivery RNASEH1, RNASE1, HNRNPA1 DGKA 3267/4885FAAH 1854/4885TSHR 833/4885
US-20260131020-A1 IONIZABLE CATIONIC LIPID FOR RNA DELIVERY SLC27A1, NSUN3, SLC10A1 DGKA 1557/4885FAAH 1291/4885TSHR 1345/4885
US-20180170866-A1 IONIZABLE CATIONIC LIPID FOR RNA DELIVERY RNASEH1, RNASE1, HNRNPA1 DGKA 3187/4885FAAH 1465/4885TSHR 922/4885
US-20180169268-A1 IONIZABLE CATIONIC LIPID FOR RNA DELIVERY RNASEH1, RNASE1, HNRNPA1 DGKA 3267/4885FAAH 1854/4885TSHR 833/4885
US-20210323914-A1 IONIZABLE CATIONIC LIPID FOR RNA DELIVERY RNASEH1, RNASE1, HNRNPA1 DGKA 3178/4885FAAH 1713/4885TSHR 941/4885
US-12637422-B2 Ionizable cationic lipid for RNA delivery POLRMT, SLC27A1, SLC43A1 DGKA 1447/4885FAAH 890/4885TSHR 1630/4885
US-12527881-B2 Ionizable cationic lipid for RNA delivery NSUN3, SLC27A1, SLC43A1 DGKA 1921/4885FAAH 1373/4885TSHR 1395/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.