Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.52 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.48 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.48 |
| ▸ | CYBB | P04839 | 5/20 | 0.46 |
| ▸ | NOX4 | Q9NPH5 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.38 |
| ▸ | ABAT | P80404 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10386782 | 0.95 | CYP2A6 (0.50) | CYP2A6CYP2A13ALDH1A1ALDH3A1ALDH1A3 | |
| SCHEMBL8627940 | 0.93 | CYP2A6 (0.48) | CYP2A6CYP2A13ALDH1A1ALDH3A1ALDH1A3 | |
| SCHEMBL9436574 | 0.93 | CYP2A6 (0.48) | CYP2A6CYP2A13ALDH1A1ALDH3A1ALDH1A3 | |
| SCHEMBL62025 | 0.89 | CYP2A6 (0.55) | CYP2A6CYP2A13ALDH1A1ALDH3A1ALDH1A3 | |
| SCHEMBL13645975 | 0.89 | CYP2A6 (0.59) | CYP2A6CYP2A13ALDH1A1ALDH3A1ALDH1A3 | |
| SCHEMBL10892510 | 0.87 | CYP2A6 (0.57) | CYP2A6CYP2A13ALDH1A1ALDH3A1ALDH1A3 | |
| SCHEMBL13645995 | 0.85 | CYP2A6 (0.64) | CYP2A6CYP2A13ALDH1A1ALDH3A1ALDH1A3 | |
| SCHEMBL24386502 | 0.84 | MAPT (0.56) | CYP2A6CYP2A13ALDH1A1ALDH3A1ALDH1A3 | |
| SCHEMBL1825553 | 0.84 | CYP2A6 (0.53) | CYP2A6CYP2A13ALDH1A1ALDH3A1ALDH1A3 | |
| SCHEMBL2314708 | 0.83 | CYP2A6 (0.48) | CYP2A6CYP2A13ALDH1A1ALDH3A1ALDH1A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240139214-A1 | AGENT FOR SUPPRESSING IL-31 PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | KYUSHU UNIVERSITY, NATIONAL UNIVERSITY CORPORATION (JP) | 2024-05-02 | — | — | US | disclosed |
| EP-4289422-A1 | AGENT FOR SUPPRESSING IL-31 PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Kyushu University, National University Corporation (JP) | 2023-12-13 | — | — | EP | disclosed |
| EP-4289422-A1 | AGENT FOR SUPPRESSING IL-31 PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | Kyushu University, National University Corporation (JP) | 2023-12-13 | — | — | EP | disclosed |
| CN-117042759-A | IL-31 production inhibitor and pharmaceutical composition containing the same | 国立大学法人九州大学 | 2023-11-10 | — | — | CN | disclosed |
| US-20230330067-A1 | NOVEL THIOHYDANTOIN DERIVATIVES AND USES THEREOF | CELROS BIOTECH (KR) | 2023-10-19 | — | — | US | disclosed |
| US-20230330067-A1 | NOVEL THIOHYDANTOIN DERIVATIVES AND USES THEREOF | CELROS BIOTECH (KR) | 2023-10-19 | — | — | US | disclosed |
| US-20230330067-A1 | NOVEL THIOHYDANTOIN DERIVATIVES AND USES THEREOF | CELROS BIOTECH (KR) | 2023-10-19 | — | — | US | disclosed |
| EP-4205740-A1 | NOVEL THIOHYDANTOIN DERIVATIVES AND USES THEREOF | Celros Biotech (KR) | 2023-07-05 | — | — | EP | disclosed |
| EP-4205740-A1 | NOVEL THIOHYDANTOIN DERIVATIVES AND USES THEREOF | Celros Biotech (KR) | 2023-07-05 | — | — | EP | disclosed |
| CN-115989060-A | Novel thiohydantoin derivatives and uses thereof | 赛罗斯生物科技 | 2023-04-18 | — | — | CN | disclosed |
| WO-2022168962-A1 | AGENT FOR SUPPRESSING IL-31 PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | 国立大学法人九州大学 | 2022-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230330067-A1 | NOVEL THIOHYDANTOIN DERIVATIVES AND USES THEREOF | NOX1, NOX4, NOX5 | CYP2A6 772/4885CYP2A13 693/4885ALDH1A1 477/4885 |
| US-20240139214-A1 | AGENT FOR SUPPRESSING IL-31 PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME | IL36G, IL1RN, IL1B | CYP2A6 556/4885CYP2A13 827/4885ALDH1A1 542/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.