Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14445423 | 0.86 | RPS6KB2 (0.45) | LMNAKMT2AMAPK1ALDH1A1GAA | |
| SCHEMBL14445422 | 0.79 | PTPRC (0.41) | LMNAKMT2AMAPK1ALDH1A1GAA | |
| SCHEMBL18430485 | 0.77 | NPC1 (0.51) | LMNAKMT2AMAPK1ALDH1A1RAB9A | |
| SCHEMBL13753721 | 0.77 | PTPRC (0.41) | LMNAMEN1KMT2AHTTMAPK1 | |
| SCHEMBL31078103 | 0.76 | KAT2B (0.46) | LMNAMEN1KMT2AHTTMAPK1 | |
| SCHEMBL6859778 | 0.74 | GPR35 (0.51) | LMNAMEN1KMT2AHTTMAPK1 | |
| SCHEMBL11537268 | 0.74 | PTPRC (0.39) | MEN1KMT2AMAPK1ALDH1A1RAB9A | |
| SCHEMBL693608 | 0.73 | PTPRC (0.45) | KMT2AMAPK1ALDH1A1GAAMAPT | |
| SCHEMBL398701 | 0.73 | LMNA (0.73) | LMNAMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL11310051 | 0.73 | LMNA (0.45) | LMNAMEN1KMT2AHTTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118302427-A | Fused ring derivative regulator, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-07-05 | — | — | CN | disclosed |
| WO-2023098880-A1 | FUSED RING DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 上海翰森生物医药科技有限公司 | 2023-06-08 | — | — | WO | disclosed |