Tyrosine

Tyrosine

SCHEMBL25286397

NC(Cc1c[nH]cn1)C(=O)O.NC(Cc1ccc(O)cc1)C(=O)O.NC(Cc1ccccc1)C(=O)O

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.60
PTGS1 P23219 2/20 0.55
ALPI P09923 1/20 0.55
PKM P14618 1/20 0.55
XIAP P98170 1/20 0.55
GRIA2 P42262 1/20 0.47
SLC1A3 P43003 1/20 0.43
SLC1A2 P43004 1/20 0.43
SLC1A1 P43005 1/20 0.43
KDM4E B2RXH2 1/20 0.43
USP2 O75604 1/20 0.43
EGFR P00533 1/20 0.43
LCK P06239 1/20 0.43
FYN P06241 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
ALOX15 P16050 1/20 0.43
HTR2A P28223 1/20 0.43
PTGS2 P35354 1/20 0.43
RECQL P46063 1/20 0.43
HIF1A Q16665 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosine SCHEMBL606712 0.96 SLC7A5 (0.65) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL28433898 0.96 SLC7A5 (0.65) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL8316690 0.96 SLC7A5 (0.65) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL606713 0.96 SLC7A5 (0.65) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL8315968 0.96 SLC7A5 (0.65) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL8904139 0.95 SLC7A5 (0.55) SLC7A5PTGS1ALPIPKMXIAP
Phenylalanine SCHEMBL638657 0.94 SLC7A5 (0.63) SLC7A5PTGS1ALPIPKMXIAP
Dl-Phenylalanine SCHEMBL1007041 0.94 SLC7A5 (0.63) SLC7A5PTGS1ALPIPKMXIAP
Tyrosine SCHEMBL28262843 0.92 SLC7A5 (0.51) SLC7A5PTGS1ALPIPKMXIAP
Histidine SCHEMBL16166274 0.91 SLC7A5 (0.47) SLC7A5PTGS1ALPIPKMXIAP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024049682-A2 PROTEINS FOR CROSS-LINKING BIOPOLYMERS ZYMERGEN INC. (US) 2024-03-07 WO disclosed
WO-2023102551-A2 FUNGAL PROTEASES, TREATED COMPOSITIONS, AND USES THEREOF SHARED-X LLC (US) 2023-06-08 WO disclosed