Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 7/20 | 0.64 |
| ▸ | CTSS | P25774 | 6/20 | 0.64 |
| ▸ | CTSL | P07711 | 4/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24113211 | 1.00 | CTSB (0.64) | CTSBCTSSCTSL | |
| SCHEMBL25286950 | 1.00 | CTSB (0.64) | CTSBCTSSCTSL | |
| SCHEMBL30310363 | 1.00 | CTSB (0.64) | CTSBCTSSCTSL | |
| SCHEMBL29062977 | 0.94 | CTSB (0.63) | CTSBCTSSCTSL | |
| SCHEMBL30008706 | 0.94 | CTSB (0.63) | CTSBCTSSCTSL | |
| SCHEMBL24020863 | 0.94 | CTSB (0.63) | CTSBCTSSCTSL | |
| SCHEMBL23824477 | 0.91 | CTSB (0.67) | CTSBCTSSCTSL | |
| SCHEMBL23824367 | 0.91 | CTSB (0.67) | CTSBCTSSCTSL | |
| SCHEMBL23824364 | 0.91 | CTSB (0.67) | CTSBCTSSCTSL | |
| SCHEMBL30008298 | 0.91 | CTSB (0.67) | CTSBCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | CTRL, CTSL, CTSV | CTSB 27/4885CTSS 7/4885CTSL 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.