Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.55 |
| ▸ | CTSB | P07858 | 3/20 | 0.55 |
| ▸ | CTSS | P25774 | 3/20 | 0.55 |
| ▸ | CTSL | P07711 | 3/20 | 0.55 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 1/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25243246 | 1.00 | CTSK (0.55) | CTSKCTSBCTSSCTSLMMP1 | |
| SCHEMBL25242835 | 0.99 | CTSK (0.56) | CTSKCTSBCTSSCTSLMMP1 | |
| SCHEMBL25289620 | 0.99 | CTSK (0.56) | CTSKCTSBCTSSCTSLMMP1 | |
| SCHEMBL25286900 | 0.96 | CTSK (0.49) | CTSKCTSBCTSSCTSLTACR1 | |
| SCHEMBL25248762 | 0.96 | CTSK (0.49) | CTSKCTSBCTSSCTSLTACR1 | |
| SCHEMBL29362725 | 0.85 | CTSL (0.49) | CTSKCTSBCTSSCTSLMMP1 | |
| SCHEMBL25289261 | 0.83 | CTSK (0.61) | CTSKCTSBCTSSCTSLCASP1 | |
| SCHEMBL25242994 | 0.83 | CTSK (0.61) | CTSKCTSBCTSSCTSLCASP1 | |
| SCHEMBL25290638 | 0.83 | CTSK (0.61) | CTSKCTSBCTSSCTSLCASP1 | |
| SCHEMBL25290639 | 0.83 | CTSK (0.61) | CTSKCTSBCTSSCTSLCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116438160-A | Carbamoyl compounds for the treatment of viral infections | 豪夫迈·罗氏有限公司 | 2023-07-14 | — | — | CN | disclosed |
| EP-4204393-A1 | AMINOCARBAMOYL COMPOUNDS FOR THE TREATMENT OF VIRAL INFECTIONS | F. Hoffmann-La Roche AG (CH) | 2023-07-05 | — | — | EP | disclosed |