Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | PDK1 | Q15118 | 5/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 5/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 5/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 5/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2529269 | 0.88 | APEX1 (0.47) | KMT2AMEN1APEX1MMP13 | |
| SCHEMBL2531949 | 0.86 | APEX1 (0.38) | KMT2AMEN1ALDH1A1MAPTAPEX1 | |
| SCHEMBL2529925 | 0.85 | APEX1 (0.37) | KMT2AMEN1ALDH1A1APEX1MMP13 | |
| SCHEMBL2528584 | 0.83 | MEN1 (0.45) | KMT2AMEN1ALDH1A1MAPTRECQL | |
| SCHEMBL2526981 | 0.82 | MEN1 (0.35) | KMT2AMEN1MMP13 | |
| SCHEMBL2526645 | 0.82 | CCR2 (0.38) | CA1CA2CA9APEX1 | |
| SCHEMBL2531504 | 0.82 | EGFR (0.43) | CA1CA2CA9KMT2AMEN1 | |
| SCHEMBL2527392 | 0.82 | APEX1 (0.47) | CA2KMT2AMEN1CA12APEX1 | |
| SCHEMBL2532676 | 0.82 | STS (0.36) | KMT2AMEN1ALDH1A1SMN1; SMN2MMP13 | |
| SCHEMBL2529810 | 0.81 | ALPL (0.45) | MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039501-B2 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2011-10-18 | — | — | US | disclosed |
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | HRH1, HRH3, HRH2 | CA1 1869/4885CA2 1756/4885CA9 1059/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.