Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.37 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.37 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.34 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2529269 | 0.91 | APEX1 (0.47) | APEX1KAT6AKAT5EGFRMEN1 | |
| SCHEMBL2529738 | 0.91 | EGFR (0.36) | KAT6AKAT5EGFRMEN1KMT2A | |
| SCHEMBL2531949 | 0.90 | APEX1 (0.38) | APEX1KAT6AKAT5EGFRMEN1 | |
| SCHEMBL2528584 | 0.88 | MEN1 (0.45) | EGFRMEN1KMT2AENPP1ENPP3 | |
| SCHEMBL2526981 | 0.87 | MEN1 (0.35) | KAT6AKAT5APPEGFRMEN1 | |
| SCHEMBL2526645 | 0.87 | CCR2 (0.38) | APEX1KAT6AKAT5CNR2 | |
| SCHEMBL2532676 | 0.87 | STS (0.36) | MEN1KMT2AMMP13ALDH1A1 | |
| SCHEMBL2528461 | 0.86 | EGFR (0.34) | KAT6AKAT5EGFRMEN1KMT2A | |
| SCHEMBL2532879 | 0.86 | AKR1C3 (0.42) | EGFRMEN1KMT2AENPP1ENPP3 | |
| SCHEMBL2528798 | 0.85 | CA1 (0.42) | APEX1MEN1KMT2AMMP13ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039501-B2 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2011-10-18 | — | — | US | disclosed |
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | HRH1, HRH3, HRH2 | APEX1 3923/4885KAT6A 1834/4885KAT5 272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.