Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HBB | P68871 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMYD2 | Q9NRG4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25283840 | 1.00 | RIPK1 (0.37) | RIPK1LMNASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL25283839 | 1.00 | RIPK1 (0.37) | RIPK1LMNASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL14564989 | 0.86 | TRPA1 (0.40) | RIPK1SLC6A4SLC6A2SLC6A3TRPA1 | |
| SCHEMBL27032153 | 0.86 | TRPA1 (0.40) | RIPK1SLC6A4SLC6A2SLC6A3TRPA1 | |
| SCHEMBL8391322 | 0.86 | TRPA1 (0.40) | RIPK1SLC6A4SLC6A2SLC6A3TRPA1 | |
| SCHEMBL23539976 | 0.85 | RIPK1 (0.35) | RIPK1LMNASLC6A4SLC6A2SLC6A3 | |
| SCHEMBL10098880 | 0.84 | RIPK1 (0.36) | RIPK1SLC6A3AOC3ALDH1A1CYP3A4 | |
| SCHEMBL4455719 | 0.83 | TRPA1 (0.35) | RIPK1SLC6A4SLC6A2SLC6A3TRPA1 | |
| SCHEMBL8175900 | 0.83 | TRPA1 (0.35) | RIPK1SLC6A4SLC6A2SLC6A3TRPA1 | |
| SCHEMBL1004941 | 0.83 | HRH1 (0.40) | RIPK1SLC6A4SLC6A2SLC6A3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023119098-A1 | PROTEIN KINASE C THETA INHIBITORS | Galderma Holding SA (CH) | 2023-06-29 | — | — | WO | disclosed |