Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA1 | P56199 | 1/20 | 0.49 |
| ▸ | ACLY | P53396 | 12/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2528064 | 0.88 | ALDH1A1 (0.39) | ITGA1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2525203 | 0.88 | ALDH1A1 (0.37) | ITGA1ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2526981 | 0.86 | MEN1 (0.35) | KAT6AKAT5MEN1KMT2A | |
| SCHEMBL2530277 | 0.84 | ALPL (0.38) | ITGA1ALDH1A1MAPTKAT6AKAT5 | |
| SCHEMBL2528541 | 0.84 | MEN1 (0.37) | MEN1KMT2A | |
| SCHEMBL2530241 | 0.84 | GAA (0.52) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2528584 | 0.83 | MEN1 (0.45) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL2532856 | 0.83 | MEN1 (0.36) | KAT6AKAT5MEN1KMT2A | |
| SCHEMBL2526409 | 0.83 | AOC3 (0.34) | ALDH1A1KAT6AKAT5MEN1KMT2A | |
| SCHEMBL2530249 | 0.82 | F2 (0.37) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039501-B2 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2011-10-18 | — | — | US | disclosed |
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | HRH1, HRH3, HRH2 | ITGA1 4689/4885ACLY 1895/4885ALDH1A1 3248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.